Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz +14 more
wiley +1 more source
Australian clinicians and chemoprevention for women at high familial risk for breast cancer
Objectives Effective chemoprevention strategies exist for women at high risk for breast cancer, yet uptake is low. Physician recommendation is an important determinant of uptake, but little is known about clinicians' attitudes to chemoprevention. Methods
Keogh Louise A +3 more
doaj +1 more source
Preventative therapies for healthy women at high risk of breast cancer [PDF]
Licensed under the Creative Commons Attribution Non-Commercial ...
Sestak, I
core +3 more sources
The immune response to malaria in utero. [PDF]
Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
The Chemopreventive Activity of Indonesia Medicinal Plants Targeting on Hallmarks of Cancer [PDF]
Cancer remains a complex disease with increasing global mortality and morbidity. Numerous theories have been established to understand the biological mechanism underlying cancer.
Edy Meiyanto, Yonika Arum Larasati
doaj +1 more source
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]
The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core +2 more sources
ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice. [PDF]
There is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries.
Li, Peng +3 more
core +2 more sources
Genomics and Discrimination in New Zealand Health and Life Insurance
The use of genomics offers substantial benefits to society by revolutionising approaches to healthcare and personalised medicine. It enables early detection of genetic predispositions to various diseases, allowing for proactive and tailored treatment plans, access to clinical trials, and improved health outcomes.
Andrew N. Shelling +3 more
wiley +1 more source
Esophageal adenocarcinoma (EAC) often develops from gastroesophageal reflux disease (GERD), with Barrett's esophagus (BE) as its main precursor. While proton pump inhibitors manage GERD symptoms, their preventive role in EAC remains unclear. This review summarizes advances in diagnosing BE and evaluates anti‐reflux surgery for its potential to prevent ...
Dagmar Kollmann +12 more
wiley +1 more source

