Results 111 to 120 of about 14,150 (254)

Physiologic regulation of heart rate and blood pressure involves connexin 36-containing gap junctions [PDF]

open access: yes, 2017
Chronically elevated sympathetic nervous activity underlies many cardiovascular diseases. Elucidating the mechanisms contributing to sympathetic nervous system output may reveal new avenues of treatment.
Ferrari A. U.   +12 more
core   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet   +6 more
wiley   +1 more source

Hemodynamic and ventilatory response to different levels of hypoxia and hypercapnia in carotid body-denervated rats

open access: yesClinics, 2013
OBJECTIVE: Chemoreceptors play an important role in the autonomic modulation of circulatory and ventilatory responses to changes in arterial O2 and/or CO2.
João Paulo J. Sabino   +5 more
doaj  

What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]

open access: yes, 2012
Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Benyhe, Sándor   +11 more
core  

Chemoreception and neuroplasticity in respiratory circuits [PDF]

open access: yes, 2017
The respiratory central pattern generator must respond to chemosensory cues to maintain oxygen (O2) and carbon dioxide (CO2) homeostasis in the blood and tissues. To do this, sensorial cells located in the periphery and central nervous system monitor the
Abdala, Ana P.   +5 more
core   +3 more sources

Defying gravity: Breath, beat and brain

open access: yes
Experimental Physiology, EarlyView.
Shigehiko Ogoh, Damian Miles Bailey
wiley   +1 more source

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr   +15 more
wiley   +1 more source

Adapt locally and act globally: strategy to maintain high chemoreceptor sensitivity in complex environments

open access: yesMolecular Systems Biology, 2011
In bacterial chemotaxis, several types of ligand‐specific receptors form mixed clusters, wherein receptor–receptor interactions lead to signal amplification and integration.
Ganhui Lan   +3 more
doaj   +1 more source

The physiology of survival: Breath‐hold shallow‐water diving

open access: yes
Experimental Physiology, EarlyView.
Andrew H. Baker   +8 more
wiley   +1 more source

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