Exponential signaling gain at the receptor level enhances signal-to-noise ratio in bacterial chemotaxis [PDF]
Peer reviewedPublisher ...
Bentele, Kajetan+7 more
core +19 more sources
Polar Chemoreceptor Clustering by Coupled Trimers of Dimers [PDF]
Receptors of bacterial chemotaxis form clusters at the cell poles, where clusters act as "antennas" to amplify small changes in ligand concentration. Interestingly, chemoreceptors cluster at multiple length scales.
Abramowitz+81 more
core +4 more sources
Protein connectivity in chemotaxis receptor complexes [PDF]
The chemotaxis sensory system allows bacteria such as Escherichia coli to swim towards nutrients and away from repellents. The underlying pathway is remarkably sensitive in detecting chemical gradients over a wide range of ambient concentrations ...
Eismann, S, Endres, RG
core +15 more sources
A pH‐sensitive chloride current in the chemoreceptor cell of rat carotid body [PDF]
1. Cardiorespiratory response to acidosis is initiated by the carotid body. 2. The direct effect of extracellular pH (pH(o)) on the chloride currents of isolated chemoreceptor cells of the rat carotid body was investigated using the whole-cell patch-clamp technique. 3. On applying intra- and extracellular solutions with a symmetrical high-Cl(-) content
Gábor L. Petheö+4 more
openaire +4 more sources
Nasal Solitary Chemoreceptor Cell Responses to Bitter and Trigeminal Stimulants In Vitro [PDF]
Nasal trigeminal chemosensitivity in mice and rats is mediated in part by epithelial solitary chemoreceptor (chemosensory) cells (SCCs), but the exact role of these cells in chemoreception is unclear. Histological evidence suggests that SCCs express elements of the bitter taste transduction pathway including T2R (bitter taste) receptors, the G protein
Brian D. Gulbransen+3 more
openaire +4 more sources
Coexpression of Galanin and Nestin in the Chemoreceptor Cells of the Human Carotid Body [PDF]
The carotid body is a highly specialized chemoreceptive organ of neural crest origin whose role is to detect changes in arterial oxygen content. The sensory units are the chemoreceptor cells, which are neuronal-like cells, surrounded by sustentacular or glial-like cells.
MAZZATENTA, ANDREA+6 more
openaire +5 more sources
Culture of arterial chemoreceptor cells from adult cats in defined medium
Recently patch clamp techniques and optical fluorometric techniques have been applied to freshly dissociated or cultured carotid body. However, very few studies have shown the effects of the dissociation and/or culture conditions on the health and function of the cells. The purpose of this study was to develop a culture method which support healthy and
Brian Schofield+3 more
openaire +4 more sources
Hydroxycobalamin Reveals the Involvement of Hydrogen Sulfide in the Hypoxic Responses of Rat Carotid Body Chemoreceptor Cells. [PDF]
Carotid body (CB) chemoreceptor cells sense arterial blood PO2, generating a neurosecretory response proportional to the intensity of hypoxia. Hydrogen sulfide (H2S) is a physiological gaseous messenger that is proposed to act as an oxygen sensor in CBs,
Gallego-Martin T+4 more
europepmc +2 more sources
Effects of osmotic changes on the chemoreceptor cell of rat carotid body
The carotid body plays a crucial role in cardiorespiratory regulation. In the present study we investigated the effect of osmotic changes on cytoplasmic calcium concentration ([Ca2+]c) and pH (pHi) of isolated chemoreceptor cells of the rat carotid body.
Gábor L. Petheö+3 more
openaire +5 more sources
HilD-regulated chemotaxis proteins contribute to <i>Salmonella</i> Typhimurium colonization in the gut. [PDF]
In the enteric pathogen Salmonella Typhimurium, invasion and motility are coordinated by HilD, a master regulator that activates expression of genes encoding the type III secretion system 1 and some motility genes, including the chemotaxis gene mcpC ...
Cooper KG+8 more
europepmc +2 more sources