Results 71 to 80 of about 7,523 (233)

Chronic exposure to perfluorooctane sulfonate induces behavior defects and neurotoxicity through oxidative damages, in vivo and in vitro. [PDF]

PLoS ONE, 2014
Perfluorooctane sulfonate (PFOS) is an emerging persistent pollutant which shows multiple adverse health effects. However, the neurotoxicity of PFOS and its mechanisms have not been fully elucidated.
Na Chen, Jia Li, Dan Li, Yongsheng Yang, Defu He   +4 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Asymmetric polar localization dynamics of the serine chemoreceptor protein Tsr in Escherichia coli. [PDF]

PLoS ONE, 2018
The spatial location of proteins in living cells can be critical for their function. For example, the E. coli chemotaxis machinery is localized to the cell poles.
Dongmyung Oh, Yang Yu, Hochan Lee, Jae-Hyung Jeon, Barry L Wanner, Ken Ritchie   +5 more
doaj   +1 more source

All Is Relative—A Call for Considering “Physiologically Informed” Control Conditions to Improve the Mechanistic Understanding of the Effects of Physical Exercise on Cognition

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT There is a growing interest in elucidating the mechanisms that drive the benefits of physical exercise on cognitive performance. A key element for a better understanding of a particular phenomenon (e.g., the mediators of the exercise‐cognition interaction) is the selection of an appropriate control condition/group as the basis for causal ...
Fabian Herold, Benjamin Tari, Sylwester Kujach, Olivier Dupuy, C. Shawn Green, Thomas Gronwald, Matthew Heath   +6 more
wiley   +1 more source

A pH‐sensitive chloride current in the chemoreceptor cell of rat carotid body [PDF]

The Journal of Physiology, 2001
1. Cardiorespiratory response to acidosis is initiated by the carotid body. 2. The direct effect of extracellular pH (pH(o)) on the chloride currents of isolated chemoreceptor cells of the rat carotid body was investigated using the whole-cell patch-clamp technique. 3. On applying intra- and extracellular solutions with a symmetrical high-Cl(-) content
G L, Petheo, Z, Molnár, A, Róka, J K, Makara, A, Spät   +4 more
openaire   +2 more sources

Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective

Experimental Physiology, EarlyView.
Abstract Cerebral blood flow (CBF) is essential for sustaining neuronal metabolism and cognitive performance; however, the precise relationship between perfusion and cognition remains unclear. Although ageing and disease are associated with progressive declines in CBF and cognitive impairment, the acute effects of altered CBF under environmental ...
Hiroki Nakata, Shigehiko Ogoh, Manabu Shibasaki   +2 more
wiley   +1 more source

Sensitive and Selective in Vitro Recognition of Biologically Toxic As(III) by Rhodamine Based Chemoreceptor

, 2019
Arsenic induced cleavage of the spirolactam ring of a cleft shaped electronically enriched rhodamine based chemoreceptor molecule 3′,6′-bis­(ethylamino)-2-((2-hydroxy-5-methylbenzylidene)­amino)-2′,7′-dimethylspiro­[isoindoline-1,9′-xanthen]-3-one ...
Samuzal Bhuyan (7120502), Subhra Kanti Mukhopadhyay (1780738), Suparna Paul (5635478), Naresh Chandra Murmu (6804794), Priyabrata Banerjee (1671088)   +4 more
core   +3 more sources

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

Experimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley, Tomoki Watada, Go Ito, Ai Shimada, Toru Sawai, Hideomi Nakata, Shingo Otsuki, Tadayoshi Miyamoto   +7 more
wiley   +1 more source

Cryo-Electron Tomography Reveals the Complex Ultrastructural Organization of Multicellular Filamentous Chloroflexota (Chloroflexi) Bacteria

Frontiers in Microbiology, 2020
The cell biology of Chloroflexota is poorly studied. We applied cryo-focused ion beam milling and cryo-electron tomography to study the ultrastructural organization of thermophilic Roseiflexus castenholzii and Chloroflexus aggregans, and mesophilic “Ca ...
Vasil A. Gaisin, Vasil A. Gaisin, Romain Kooger, Denis S. Grouzdev, Vladimir M. Gorlenko, Martin Pilhofer   +5 more
doaj   +1 more source

In Vivo Crosslinking Methods for Analyzing the Assembly and Architecture of Chemoreceptor Arrays [PDF]

, 2007
The chemoreceptor molecules that mediate chemotactic responses in bacteria and archaea are physically clustered and operate as highly cooperative arrays.
John S. Parkinson, Claudia A. Studdert, Parkinson, John S., Studdert, Claudia Alicia   +3 more
core   +1 more source