Results 81 to 90 of about 60,935 (266)

A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing [PDF]

, 2008
Acid-sensitive K+ channels of the tandem P-domain K+-channel family (TASK-1 and TASK-3) have been implicated in peripheral and central respiratory chemosensitivity; however, because of the lack of decisive pharmacological agents, the final proof of the ...
Gourine, A. V., Isabel Aller, M., Trapp, S., Wisden, W.   +3 more
core   +1 more source

Location and architecture of the Caulobacter crescentus chemoreceptor array [PDF]

, 2008
A new method for recording both fluorescence and cryo-EM images of small bacterial cells was developed and used to identify chemoreceptor arrays in cryotomograms of intact Caulobacter crescentus cells.
Alexander, Alley, Alley, Alley, Ames, Ames, Ames, Ausmees, Berg, Bilwes, Boldog, Boukhvalova, Bourret, Bray, Bray, Briegel, Djordjevic, Djordjevic, Djordjevic, Ely, Falke, Francis, Francis, Gestwicki, Gomes, Griswold, Iancu, Iancu, Jensen, Jensen, Kim, Lefman, Levin, Li, Li, Li, Lipkow, Lucic, Lybarger, Maddock, Mastronarde, Park, Parkinson, Sartori, Schwartz, Shaw, Shimizu, Sourjik, Sourjik, Studdert, Studdert, Tsay, Wagner, Weis, Weis, Wolanin, Wright, Zhang, Zhang, Zheng   +59 more
core   +1 more source

Conformational coupling between receptor and kinase binding sites through a conserved salt bridge in a signaling complex scaffold protein. [PDF]

PLoS Computational Biology, 2013
Bacterial chemotaxis is one of the best studied signal transduction pathways. CheW is a scaffold protein that mediates the association of the chemoreceptors and the CheA kinase in a ternary signaling complex.
Davi R Ortega, Guoya Mo, Kwangwoon Lee, Hongjun Zhou, Jerome Baudry, Frederick W Dahlquist, Igor B Zhulin   +6 more
doaj   +1 more source

Chemical sensing by cell-surface chemoreceptor arrays: the roles of receptor cooperativity and adaptation [PDF]

arXiv, 2012
Most sensory cells use cross-membrane chemoreceptors to detect chemical signals in the environment. The biochemical properties and spatial organization of chemoreceptors play important roles in achieving and maintaining sensitivity and accuracy of chemical sensing.
arxiv  

Surface activity of cancer cells: the fusion of two cell aggregates [PDF]

arXiv, 2021
Although a good comprehension of how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been generated, the impact of collective migration on cellular rearrangement from subcellular to supracellular level remains less understood.
arxiv  

Born high, born fast: Does highland birth confer a pulmonary advantage for sea level endurance?

Experimental Physiology, EarlyView.
Abstract Less than 7% of the world's population live at an altitude above 1500 m. Yet, as many as 67% of medalists in the 2020 men's and women's Olympic marathon, and 100% of medalists in the 2020 men's and women's Olympic 5000 m track race may have been born or raised above this otherwise rare threshold.
Hunter L. Paris, Marissa N. Baranauskas, Keren Constantini, Ren‐Jay Shei, Peyton E. Allen, John R. Jadovitz, Chad C. Wiggins, Cooker Perkins Storm   +7 more
wiley   +1 more source

Sensory Processing and Integration at the Carotid Body Tripartite Synapse: Neurotransmitter Functions and Effects of Chronic Hypoxia

Frontiers in Physiology, 2018
Maintenance of homeostasis in the respiratory and cardiovascular systems depends on reflexes that are initiated at specialized peripheral chemoreceptors that sense changes in the chemical composition of arterial blood.
Erin M. Leonard, Shaima Salman, Colin A. Nurse   +2 more
doaj   +1 more source

Topological and functional characterization of an insect gustatory receptor. [PDF]

PLoS ONE, 2011
Insect gustatory receptors are predicted to have a seven-transmembrane structure and are distantly related to insect olfactory receptors, which have an inverted topology compared with G-protein coupled receptors, including mammalian olfactory receptors ...
Hui-Jie Zhang, Alisha R Anderson, Stephen C Trowell, A-Rong Luo, Zhong-Huai Xiang, Qing-You Xia   +5 more
doaj   +1 more source

Salmonella chemoreceptors McpB and McpC mediate a repellent response to L-cystine: a potential mechanism to avoid oxidative conditions [PDF]

Lazova, M. D., Butler, M. T., Shimizu, T. S., and Harshey, R. M., Salmonella chemoreceptors McpB and McpC mediate a repellent response to L-cystine: a potential mechanism to avoid oxidative conditions. Mol Microbiol 84 (4), 697 (2012), 2013
Chemoreceptors McpB and McpC in Salmonella enterica have been reported to promote chemotaxis in LB motility-plate assays. Of the chemicals tested as potential effectors of these receptors, the only response was towards L-cysteine and its oxidized form, L-cystine.
arxiv  

Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas

Experimental Physiology, EarlyView.
Abstract Moderate and acute intermittent hypoxia (IH) facilitates respiration in adults, mostly by recruiting peripheral chemo‐/baroreceptors. As central chemoreceptors are widely expressed in immature brains, we hypothesized that IH modulates respiration at birth through a purely neurogenic mechanism involving the hypothalamus.
Rosamaria Apicella, Graciela L. Mazzone, Giuliano Taccola   +2 more
wiley   +1 more source