Results 161 to 170 of about 133,761 (337)

Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll‐like receptor 4‐dependent macrophage activation in asthma

Animal Models and Experimental Medicine, EarlyView.
The alleviation of asthma by polydatin is dependent on the blockage of the toll‐like receptor 4 (TLR4)/P2X7R synergy in macrophages. The blockage of the TLR4/P2X7R synergy results in decreased release and secretion of interleukin‐1β (IL‐1β) and IL‐18. In epithelial cells, low IL‐1β and IL‐18 levels inhibit mitochondrial damage and apoptosis.
Guangxing Li, Ruobai Liu, Chang Xu, Jianing Yang, Yilan Song, Li Li, Jingzhi Jiang, Liangchang Li, Chongyang Wang, Guanghai Yan   +9 more
wiley   +1 more source

Structure-Activity Relationship (SAR) as a Weapon Against Chemoresistance in Pancreatic Cancer [PDF]

Md Abubakar
openalex   +1 more source

Bioinformatics‐based discovery of the involvement of PSAT1 in mediating the anti‐lung adenocarcinoma activity of triptolide

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing was performed on tumor tissues from triptolide‐treated tumor‐bearing mice. The sequencing results were integrated with data from public databases for comprehensive analysis, and potential regulatory targets of triptolide were identified.
Zhiwen Cao, Lulu Zhang, Wenqiang Zhang, Rong Wan, Xiaogang Peng, Jinyan Xie, Ruru Bai, Jiejing Jin, Changqi Shi, Lan Yan, Xiangyu Guo, Yang Shen, Cheng Lu   +12 more
wiley   +1 more source

A TAZ–ANGPTL4–NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer

, 2019
Wen‐Hsuan Yang, Zhiqing Huang, Jianli Wu, Chien‐Kuang Cornelia Ding, Susan K. Murphy, Jen‐Tsan Chi   +5 more
openalex   +2 more sources

Expression of the multidrug resistance‐associated protein (MRP) and chemoresistance of human non‐small‐cell lung cancer cells [PDF]

, 1997
Walter Berger, Leonilla Elbling, Erich Hauptmann, M. Micksche   +3 more
openalex   +1 more source

Overcoming chemoresistance [PDF]

Nature Reviews Drug Discovery, 2019
openaire   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

Therapeutic targeting potential of the protein lysine and arginine methyltransferases to reverse cancer chemoresistance

Frontiers in Molecular Biosciences
Cancer treatments have continued to improve tremendously over the past decade, but therapy resistance is still a common, major factor encountered by patients diagnosed with cancer.
Isaac Micallef, Isaac Micallef, Kimberly Fenech, Byron Baron   +3 more
doaj   +1 more source

YAP Promotes Chemoresistance to 5-FU in Colorectal Cancer Through mTOR/GLUT3 Axis [PDF]

Qixuan Xu, Zhen Jin, Zhen Yuan, Zhiyuan Yu, Jingwang Gao, Ruiyang Zhao, Hanghang Li, Huiguang Ren, Bo Cao, Bo Wei, Lin‐Hua Jiang   +10 more
openalex   +1 more source

Editorial Comment on: DPP9 Increases Chemoresistance and is an Indicator of Poor Prognosis in Colorectal Cancer [PDF]

, 2020
Takehiko Yokobori
openalex   +1 more source