Results 201 to 210 of about 133,761 (337)

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

ARTS Confers Chemoresistance of Breast Cancer by Inducing Apoptosis-Dependent Autophagy via Livin-MDM2-p53 Pathway. [PDF]

Research (Wash D C)
Wang H, Guo Q, Shen Y, Ding K, Chen Y, Wang X, Huang X, Wu Z.   +7 more
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

Heat shock factor 1 promotes proliferation and chemoresistance in diffuse large B-cell lymphoma by enhancing the cell cycle and DNA repair [PDF]

Fang Yu, Liang Cheng, Ming Huang, Yi Cao, Qihua Zou, Jun Cai, Yuchen Zhang, Yi Xia, Huiqiang Huang, Xu Chen, Qingqing Cai   +10 more
openalex   +1 more source

Data from Lentiviral short hairpin RNA screen of genes associated with multidrug resistance identifies PRP-4 as a new regulator of chemoresistance in human ovarian cancer

, 2023
Zhenfeng Duan, Edward J. Weinstein, Diana Ji, Rachel Y. Ames, Edwin Choy, Henry J. Mankin, Francis J. Hornicek   +6 more
openalex   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

The translation factor eIF4E is a key mediator of doxorubicin resistance: insights from a triple-negative breast cancer model. [PDF]

Sci Rep
Frayde-Gómez H, Chimal-Vega B, Pulido-Capiz A, Muñoz-Ayala A, Galindo-Hernández O, Vique-Sanchez JL, Leija-Montoya AG, Díaz-Molina R, Madero-Ayala PA, Ramos-Ibarra MA, García-González V.   +10 more
europepmc   +1 more source

HMGB1 Assists in Overcoming Cisplatin Resistance in Chemoresistant Human Ovarian Cancer Cells

Molecular Carcinogenesis, EarlyView.
ABSTRACT Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes.
Van Huynh, Guliang Wang, Anirban Mukherjee, Karen M. Vasquez   +3 more
wiley   +1 more source

Exploring cisplatin resistance in ovarian cancer through integrated bioinformatics approach and overcoming chemoresistance with sanguinarine.

, 2020
Lihua Yang, Hongbo Zhao, Xueqin Yin, Hong Liang, Zhi Zheng, Qiang Shen, Wanqin Hu   +6 more
openalex   +1 more source

Shear stress regulation of stemness, chemoresistance and tumor-mesothelial interaction in ovarian cancer

, 2018
Shanshan Li
openalex   +1 more source