Results 221 to 230 of about 78,550 (267)

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Knocking down CLDN7 enhanced the effect of cisplatin in OC cells by regulating mitophagy. [PDF]

J Ovarian Res
Zheng X, Hu B, Xu Q, Wang L, Han B, Wang K.   +5 more
europepmc   +1 more source

Reversing Bladder Cancer Chemo-resistance through Blocking Cell Senescence by a Combination Therapy. [PDF]

Theranostics
He Y, Fang Z, Zhang J, Wei Q, Li Y, Duan Z, Xu G, Lin T, Xiong Q, Gong Q, Tan P, Luo K.   +11 more
europepmc   +1 more source

Acquired resistance of cancer therapies: Mechanisms and perspectives. [PDF]

Chin Med J (Engl)
Wang M, Zhai X, Li J, Chen J, Gai X, Liu X, Liu Y, Zhou Q, Chen C.   +8 more
europepmc   +1 more source

Chemoresistance in gonorrhea.

Acta dermato-venereologica, 2010
openaire   +1 more source

Targeting senescence-like tumor-associated macrophages sensitizes chemotherapy in triple-negative breast cancer. [PDF]

Cell Oncol (Dordr)
Zhou H, Xu C, Zhang J, Liu Y, Gao X, He Z, Wu Y, Zhao Q, Liang B, Song D.   +9 more
europepmc   +1 more source

Unraveling glutamine metabolism in ovarian carcinoma: signaling cross-talk, positron emission tomography utility, and therapeutic boundaries. [PDF]

Transl Cancer Res
Tong J.
europepmc   +1 more source

SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research. [PDF]

J Exp Clin Cancer Res
Kong X, Lei L, Jin L, Ren C, Mi T, Wang Q, He D.   +6 more
europepmc   +1 more source