Results 231 to 240 of about 136,885 (362)

Supplementary Figure S6 from Targeted Therapy to β3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases

, 2023
Gregory C. Fox, Xinming Su, Jennifer L. Davis, Yalin Xu, Kristin A. Kwakwa, Michael H. Ross, Francesca Fontana, Jingyu Xiang, Alison K. Esser, Elizabeth Cordell, Kristen Pagliai, Ha X. Dang, Jothilingam Sivapackiam, Sheila A. Stewart, Christopher A. Maher, Suzanne J. Bakewell, James A. J. Fitzpatrick, Vijay K. Sharma, Samuel Achilefu, Deborah J. Veis, Gregory M. Lanza, Katherine N. Weilbaecher   +21 more
openalex   +1 more source

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

The Journal of Pathology, EarlyView.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen, Satu Tiainen, Jouni Kujala, Linnea Muhonen, Ponnuswamy Mohanasundaram, Tuomas Tikkanen, Ina Pöhner, Tommi Patinen, Simone Adinolfi, Juha P Väyrynen, Päivi Auvinen, Arto Mannermaa, Petri Pölönen, Tuomas Rauramaa, Anna‐Liisa Levonen   +14 more
wiley   +1 more source

Targeting senescence-like tumor-associated macrophages sensitizes chemotherapy in triple-negative breast cancer. [PDF]

Cell Oncol (Dordr)
Zhou H, Xu C, Zhang J, Liu Y, Gao X, He Z, Wu Y, Zhao Q, Liang B, Song D.   +9 more
europepmc   +1 more source

Role of miR-27a, miR-181a and miR-20b in gastric cancer hypoxia-induced chemoresistance [PDF]

, 2016
Katia Danza, Nicola Silvestris, Giovanni de Simone, M. Signorile, Luca Saragoni, Oronzo Brunetti, Manlio Monti, Annalisa Mazzotta, Simona De Summa, Anita Mangia, Stefania Tommasi   +10 more
openalex   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

NRF2 Drives Aggressiveness and Chemoresistance in Ovarian Cancer Stem-like Cells. [PDF]

Int J Mol Sci
Chang YH, Wang KH, Ding DC.
europepmc   +1 more source

Additional file 6: Figure S6. of Gonadotropin-mediated chemoresistance: Delineation of molecular pathways and targets

, 2015
Suchismita Sahoo, Poonam Singh, Beneeta Kalha, O. P. Singh, Rahul Pal   +4 more
openalex   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research. [PDF]

J Exp Clin Cancer Res
Kong X, Lei L, Jin L, Ren C, Mi T, Wang Q, He D.   +6 more
europepmc   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source