Results 251 to 260 of about 136,885 (362)

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

LRRC8A Inhibition Overcomes Chemoresistance by Downregulating MRP3 and CYP3A4 in the 3D Spheroid Model of Human Breast Cancer Cells. [PDF]

Int J Mol Sci
Otsuka R, Kajikuri J, Matsui M, Kito H, Kitahara A, Mitsui H, Yamaguchi Y, Hisada T, Toyama T, Ohya S.   +9 more
europepmc   +1 more source

SKI-II reverses the chemoresistance of SGC7901/DDP gastric cancer cells

, 2014
Ying Liu, ZUAN ZHU, Hongxing Cai, Qinghua Liu, Honglian Zhou, Zhengqiu Zhu   +5 more
openalex   +2 more sources

Circulating tumour cells (CTCs) in haematological malignancies: Advances in biology and clinical relevance with a focus on multiple myeloma

British Journal of Haematology, EarlyView.
Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu, Jui‐Feng Hsu, Jee‐Fu Huang, Yi‐Chang Liu   +3 more
wiley   +1 more source

SERBP1 is required for efficient HR repair and cisplatin chemoresistance in lung adenocarcinoma. [PDF]

Cell Death Discov
Xie Y, Chen Q, Tang N, Zeng Y, Zhao J, Yang Y, Li C, Li J, Zhu J, Huang JA, Liu Z.   +10 more
europepmc   +1 more source

Evaluation of the potential of overcoming the chemoresistance of melanoma to BRAFV600E (Vemurafenib) and MEK (Trametinib) inhibitors using combinatory therapy with 4-nerolidylcatechol (4-NC)

, 2018
Débora Kristina Alves Fernandes
openalex   +1 more source

FOXM1 and CHD4 expression is associated with chemoresistance in hepatoblastoma

Yuko Hino, Kenichi Kohashi, Akihiko Tamaki, Naonori Kawakubo, Hiroshi Hamada, Masahiro Fukuhara, Yuichi Shibui, Tatsuro Tajiri, Yoshinao Oda   +8 more
openalex   +1 more source

Chemotherapy‐driven expression of WNT ligands in bone marrow stromal cells contributes to chemoresistance in acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Chemotherapy‐induced WNT ligand secretion by bone marrow (BM) stroma drives acute lymphoblastic leukaemia (ALL) chemoresistance. WNT pathway inhibition disrupts this cross‐talk and restores therapeutic response, highlighting WNT inhibitors as a promising strategy to prevent relapse in ALL.
Foteini Kalampalika, Amanda Jiménez‐Pompa, Raúl Sánchez‐Lanzas, Bela Patel, Miguel Ganuza   +4 more
wiley   +1 more source

Microbiome Modulation with <i>Lactobacillus rhamnosus</i> GG Potentiates Curcumin's Efficacy in Reversing Gemcitabine Resistance of Gallbladder Cancer through Gut Microbiota-PI3K/AKT Axis. [PDF]

J Microbiol Biotechnol
Li Y, Niu S, Wang H, Li J.
europepmc   +1 more source

MicroRNA-215 is upregulated by treatment with Adriamycin and leads to the chemoresistance of hepatocellular carcinoma cells and tissues

, 2015
Li Wang, Yan Ming Wang, Song Xu, Wei Guo Wang, Yang Chen, JING YU MAO, Bo Tian   +6 more
openalex   +2 more sources