Abstract Non‐functioning pancreatic neuroendocrine tumors (NF‐pNETs) significantly contribute to the premature death of multiple endocrine neoplasia type 1 (MEN1) patients. Reliable prognostic markers are not yet available. MicroRNAs (miRNA) and long‐non‐coding (lnc) RNAs, transported by extracellular vesicles, are emerging as new prognostic tools ...
Jerena Manoharan+12 more
wiley +1 more source
Exploring the therapeutic potential of "Zhi-Zhen" formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, network pharmacology, and experimental validation. [PDF]
Li Y+6 more
europepmc +1 more source
Non‐Anticoagulant Heparin: An In Vitro Investigation of a Novel Therapeutic Approach for Oral Cancer
ABSTRACT Background Oral squamous cell carcinoma (OSCC) represents a significant global oral health concern. Non‐anticoagulant heparin (NH) emerges as a promising solution considering the enhanced survival observed with anticoagulants in cancer treatment. Methods We used the MTS assay (0/24/48/72 h), scratch assay (MuviCyte, 0–18 h), invasion Matrigel (
S. A. Hamza+6 more
wiley +1 more source
WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancer. [PDF]
Wang Y+13 more
europepmc +1 more source
Tumor–Stroma Ratio in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta‐Analysis
ABSTRACT Background Tumor‐stroma ratio (TSR) has been recognized as a significant prognostic factor in various cancers. This systematic review evaluates the role of TSR in head and neck squamous cell carcinoma (HNSCC) and its association with patient outcomes such as overall survival (OS), disease‐free survival (DFS), disease‐specific survival (DSS ...
Gennaro Musella+6 more
wiley +1 more source
Hydrogel-mediated mitochondrial reprogramming for inducing cell death: a novel approach to overcoming gemcitabine resistance in pancreatic ductal adenocarcinoma. [PDF]
Zhao Q+9 more
europepmc +1 more source
PFAS are widespread environmental contaminants that are associated with platinum resistance and mitochondrial membrane hyperpolarization in endometrial cancer cell lines. Photodynamic therapy, using BPD or ALA‐PpIX, in combination with low‐dose carboplatin overcomes PFAS‐induced platinum resistance in endometrial cancer cell lines.
Brittany P. Rickard+7 more
wiley +1 more source
Retraction notice: "MicroRNA-19b Downregulates NR3C1 and Enhances Oxaliplatin Chemoresistance in Colon Cancer via the PI3K/AKT/mTOR Pathway". [PDF]
europepmc +1 more source