Results 341 to 350 of about 149,400 (379)

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer, accounting for approximately 70% of all ovarian cancer cases and contributing significantly to the high mortality rates associated with this disease.
Pawel Kordowitzki, Britta Lange, Kevin M. Elias, Marcia C. Haigis, Sylvia Mechsner, Ioana Elena Braicu, Jalid Sehouli   +6 more
wiley   +1 more source

RIP2/NF-κB/PD-L1 signaling pathway is involved in temozolomide resistance by inducing autophagy in glioblastoma cells. [PDF]

Transl Oncol
Liu X, Liu X, Zhao L, Wu J, Wang X, Hu Y.   +5 more
europepmc   +1 more source

Cell lineage tracing: Methods, applications, and challenges

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cell lineage tracing is a crucial technique for understanding cell fate and lineage relationships, with wide applications in developmental biology, tissue regeneration, and disease progression studies. Over the years, experimental cell lineage tracing methods have advanced from early labeling techniques to modern genetic tools such as CRISPR ...
Shanjun Mao, Chenyang Zhang, Runjiu Chen, Shan Tang, Xiaodan Fan, Jie Hu   +5 more
wiley   +1 more source

Role of M2 macrophage-derived exosomes in cancer drug resistance via noncoding RNAs. [PDF]

Discov Oncol
Hu X, Li Y, Wang X, Xue X.
europepmc   +1 more source

A comprehensive analysis of the relationship between inflammasomes and autophagy in human tumors: Recent developments

Journal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.
The interaction between inflammasomes and autophagy is crucial for maintaining the balance between necessary immune responses and the avoidance of excessive inflammation. Autophagy can inhibit the activation of the NLRP3 inflammasome by degrading endogenous activators, such as damaged mitochondria that produce reactive oxygen species (ROS), as well as ...
Sai Liu, Jingzhou Zhang
wiley   +1 more source

In vivo functional screens reveal <i>KEAP1</i> loss as a driver of chemoresistance in small cell lung cancer. [PDF]

Sci Adv
Brumage L, Best S, Hippe DS, Grunblatt E, Chanana P, Wu F, Lee MC, Ying Z, Ibrahim A, Chung JH, Vigil A, Fatherree J, Beronja S, Paddison P, Sullivan L, Nabet B, MacPherson D.   +16 more
europepmc   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

MedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi, Izuchukwu F. Okpalanwaka, Adenike Oyegbesan, Ebenezar Okoyeocha, Mariam Oladejo, Sikiru O. Imodoye   +5 more
wiley   +1 more source

Hyaluronan-mediated motility receptor-mediated aerobic glycolysis enhances stem-like properties and chemoresistance in lung adenocarcinoma. [PDF]

Korean J Physiol Pharmacol
Yu W, Shi Y, Bao X, Chen X, Ni Y, Wang J, Ye H.   +6 more
europepmc   +1 more source

Induction of ferroptosis in oxaliplatin-resistant colorectal cancer cells by extract from <i>Actinidia chinensis</i> Planch radix. [PDF]

Transl Cancer Res
Lu J, Wang Y, Cui W, Ma C.
europepmc   +1 more source

TRIM29 upregulation contributes to chemoresistance in triple negative breast cancer via modulating S100P-β-catenin axis. [PDF]

Cell Commun Signal
Wu Q, Siddharth S, Verma D, Parida S, Sharma D.   +4 more
europepmc   +1 more source