Results 181 to 190 of about 77,751 (291)

Lysosomal enzyme release from neutrophils from the patients with Behçet's disease by chemotactic factors

open access: bronze, 1982
Akiteru Takeuch   +5 more
openalex   +2 more sources

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen   +9 more
wiley   +1 more source

Regulation of cytokine expression and leukotriene formation in human basophils by growth factors, chemokines and chemotactic agonists [PDF]

open access: bronze, 1999
B Ochensberger   +4 more
openalex   +1 more source

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

open access: yesThe FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source

Human tissue kallikrein 14 induces the expression of IL‐6, IL‐8, and CXCL1 in skin fibroblasts through protease‐activated receptor 1 signaling

open access: yesThe FEBS Journal, EarlyView.
Human tissue kallikrein 14 (KLK14), a skin protease, may mediate paracrine signaling in wound healing. KLK14 released by epithelial cells activates fibroblasts via PAR‐1 activation, inducing IL‐6, IL‐8, and CXCL1 expression. These cytokines in turn promote keratinocyte proliferation and migration, resulting in wound closure.
Laura Sasiadek   +16 more
wiley   +1 more source

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