Results 181 to 190 of about 133,222 (232)

Coordination of Neutrophil and Apoptosis-Inducing Ligand in Inflammatory Diseases. [PDF]

open access: yesJ Inflamm Res
Xue H   +7 more
europepmc   +1 more source

CXCL10highTNFαhighKi67+ Microglia Recruit and Activate CD8+ T Cells in the Brainstem During Experimental Cerebral Malaria

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.
Microglia exhibit distinct transcriptional and morphological heterogeneity in experimental cerebral malaria (ECM) compared to physiological microglia. A unique subtype of ECM‐associated microglia, characterized by CXCL10highTNFαhighKi67+, mediates the recruitment and sustained activation of CD8+ T cells through ongoing interactions, exacerbating ...
Yi Wang   +13 more
wiley   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

open access: yesDiabetic Medicine, Volume 42, Issue 6, June 2025.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey   +7 more
wiley   +1 more source

Experimental Drought Suppresses Amphibian Pathogen Yet Intensifies Transmission and Disrupts Protective Skin Microbiome

open access: yesGlobal Change Biology, Volume 31, Issue 6, June 2025.
This study used ecologically realistic enclosures with pumpkin toadlets to simulate short‐term drought conditions in Brazil's Atlantic Forest. Drought reduced the overall levels of a harmful amphibian fungus, but it also disrupted their protective skin‐associated bacteria and caused the toadlets to cluster in wet areas of the enclosures, which ...
Shannon Buttimer   +9 more
wiley   +1 more source

The RNA‐Binding Proteins MCPIP2 and IGF2BP1 Competitively Modulate Breast Tumor Angiogenesis by Antagonizing VEGFA mRNA Stability and Expression

open access: yesThe FASEB Journal, Volume 39, Issue 10, 31 May 2025.
A proposed model showed that the RNA binding proteins MCPIP2 and IGF2BP1 competitively regulate the stability and expression of proangiogenic transcripts in tumor cells. MCPIP2 decays proangiogenic mRNAs by binding to the conserved stem–loop structure in the 3ʹ UTR via its RNase domain, resulting in inhibition of proangiogenic gene expression and ...
Wenbao Lu   +4 more
wiley   +1 more source

The role of CXC chemokines and receptors in breast cancer. [PDF]

open access: yesClin Exp Med
Masrour M   +4 more
europepmc   +1 more source

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