Results 241 to 250 of about 77,751 (291)

Effective Macroscopic Equations for Biological Fluid and Nutrients' Transport in Vascularized Tumors Growing Via Proliferation and Chemotaxis

open access: yesMathematical Methods in the Applied Sciences, Volume 48, Issue 14, Page 13285-13299, 30 September 2025.
ABSTRACT This paper presents a system of partial differential equations designed to model fluid and nutrient transport within the growing tumor microenvironment. The fluid phase, representing both cells and extracellular fluids flowing within the interstitial space, is assumed to be intrinsically incompressible, so that growth can be modeled as a ...
Francesca Ballatore   +2 more
wiley   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

Enhanced diagnostic potential of CSPG4 in melanoma and nevi: a comparative study with PRAME, CDC7 and Ki67

open access: yesThe Journal of Pathology, Volume 267, Issue 1, Page 69-78, September 2025.
Abstract Chondroitin sulfate proteoglycan 4 (CSPG4) is a promising target for melanoma immunotherapy, but its expression in benign melanocytic lesions and its diagnostic value remain unexplored. This study assessed CSPG4 expression in benign nevi (BN), dysplastic nevi (DN), and superficial spreading melanomas (SSM), comparing it with PRAME ...
Elias AT Koch   +8 more
wiley   +1 more source

Enhanced homing and efficacy of HER2-CAR T cells via CXCR5/CCR6 co-expression for HER2-positive NSCLC. [PDF]

open access: yesJ Transl Med
Hu X   +12 more
europepmc   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut   +1 more
wiley   +1 more source

14. Discogenic Low Back Pain

open access: yesPain Practice, Volume 25, Issue 7, September 2025.
ABSTRACT Introduction Discogenic low back pain can be severely disabling, clinically challenging to diagnose, and expensive to treat. Disc degeneration is characterized by disc dehydration, which diminishes the ability of the disc to distribute pressure, making it more susceptible to damage, and leading to annular tears, fissures, and a higher ...
Wouter K. M. van Os   +6 more
wiley   +1 more source

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