Results 21 to 30 of about 77,751 (291)

Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status. [PDF]

open access: yesPLoS ONE, 2017
The identification of immune correlates that are predictive of disease outcome for tuberculosis remains an ongoing challenge. To address this issue, we evaluated gene expression profiles from peripheral blood mononuclear cells following ex vivo challenge
Elaine A Yu   +6 more
doaj   +1 more source

Endothelin-1 Stimulates Monocytes in vitro to Release Chemotactic Activity Identified as Interleukin-8 and Monocyte Chemotactic Protein-1

open access: yesMediators of Inflammation, 1994
In the present study we examined whether endothelin-1 stimulation of human monocytes causes release of chemotactic factors. It was found that monocytes released neutrophil- and monocyte-chemotactic activity in a dose- and time-dependent manner in ...
E. Helset, T. Sildnes, Z. S. Konopski
doaj   +1 more source

A Chemotactic Factor for Mononuclear Leukocytes

open access: yesExperimental Biology and Medicine, 1971
SummaryChemotactic activity for mononuclear leukocytes was produced when highly purified guinea pig C5 was cleaved by trypsin or by the earlier acting complement components. This chemotactic activity was mediated by C5a, a fragmentation product of the fifth component of complement.
Ralph Snyderman   +2 more
openaire   +3 more sources

AN EOSINOPHIL LEUKOCYTE CHEMOTACTIC FACTOR OF ANAPHYLAXIS [PDF]

open access: yesThe Journal of Experimental Medicine, 1971
The capacity of actively or passively sensitized guinea pig lung to react with antigen to release a factor specifically chemotactic for eosinophil leukocytes (ECF-A) has been demonstrated. The release of ECF-A was also accompanied by the elaboration of both histamine and SRS-A and the appearance of all these mediators exhibited a similar response in ...
Daniel J. Stechschulte   +2 more
openaire   +3 more sources

Damaged male germ cells induce epididymitis in mice

open access: yesAsian Journal of Andrology, 2020
Epididymitis can be caused by infectious and noninfectious etiological factors. While microbial infections are responsible for infectious epididymitis, the etiological factors contributing to noninfectious epididymitis remain to be defined.
Wei-Hua Liu   +10 more
doaj   +1 more source

Contribution of corneal neovascularization to dendritic cell migration into the central area during human corneal infection. [PDF]

open access: yesPLoS ONE, 2014
Compared with the peripheral corneal limbus, the human central cornea lacks blood vessels, which is responsible for its immunologically privileged status and high transparency.
Mari Narumi   +5 more
doaj   +1 more source

Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration.

open access: yesPLoS ONE, 2019
BackgroundAfter bone resorption, ions and degraded organic components are co-released into the extracellular space. Ions and growth factors, although different in their biological nature, induce a common and coordinated chemotactic effect.
Rubén Aquino-Martínez   +2 more
doaj   +1 more source

Cytokine concentration in peripheral blood of patients with colorectal cancer

open access: yesFrontiers in Immunology, 2023
IntroductionThe role of tumour secretory cytokines and peripheral circulatory cytokines in tumour progression has received increasing attention; however, the role of tumour-related inflammatory cytokines in colorectal cancer (CRC) remains unclear.
Wenchang Li   +35 more
doaj   +1 more source

Associations Between Macrophage Colony‐Stimulating Factor and Monocyte Chemotactic Protein 1 in Plasma and First‐Time Coronary Events: A Nested Case–Control Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Myeloid cells play a central role in atherosclerosis. We investigated the associations between the plasma levels of growth factors and chemokines that regulate myeloid cell homeostasis and function and the risk of first‐time acute coronary ...
Alexandru Schiopu   +5 more
doaj   +1 more source

Intranasal administration of human MSC for ischemic brain injury in the mouse: in vitro and in vivo neuroregenerative functions. [PDF]

open access: yesPLoS ONE, 2014
Intranasal treatment with C57BL/6 MSCs reduces lesion volume and improves motor and cognitive behavior in the neonatal hypoxic-ischemic (HI) mouse model.
Vanessa Donega   +6 more
doaj   +1 more source

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