Results 71 to 80 of about 133,222 (232)

Selenium‐Containing Polyurethane Thermo‐Sensitive Hydrogel Accelerates Diabetic Wound Healing by Activating Unfolded Protein Response

open access: yesAggregate, EarlyView.
The selenium‐containing polyurethane (SePU) thermo‐sensitive hydrogel (SePU/HBC) was constructed by incorporating SePU into hydroxybutyl chitosan (HBC). This hydrogel alleviates endoplasmic reticulum stress (ERS) and inhibits cell apoptosis by activating the unfolded protein response (UPR), thereby promoting diabetic wound healing.
Mo Zhai   +8 more
wiley   +1 more source

Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages. [PDF]

open access: yes, 2018
Macrophage migration is an essential step in host defense against infection and wound healing. Elevation of cAMP by inhibiting phosphodiesterase 4 (PDE4), enzymes that specifically degrade cAMP, is known to suppress various inflammatory responses in ...
Catherine Jin, S-L   +7 more
core  

Differentiated cell behavior: a multiscale approach using measure theory

open access: yes, 2014
This paper deals with the derivation of a collective model of cell populations out of an individual-based description of the underlying physical particle system.
Colombi, Annachiara   +2 more
core   +1 more source

Biomimetic Chemotactic Motion of Self‐Assembling Doublet Microrobots

open access: yesAdvanced Intelligent Systems, EarlyView.
This article studies the shape‐dependent chemotaxis of different morphologies including self‐assembled doublet microswimmers that exhibit autonomous movement in hydrogen peroxide H2O2 gradients. Without the need for complex material preparation a novel type of chemotactic active matter is produced, which allows the separation of propulsion and cargo ...
Zuyao Xiao   +2 more
wiley   +1 more source

Cell-to-cell variation sets a tissue-rheology-dependent bound on collective gradient sensing

open access: yes, 2017
When a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a fundamental limit to the cell's accuracy. For clusters of cells responding to gradients, however, there is a critical difference: even genetically ...
Camley, Brian A., Rappel, Wouter-Jan
core   +1 more source

Associations of Historic Residential Pesticide Proximity With Proinflammatory Cytokine Levels in a Patient Population With and Without Chronic Rhinosinusitis (CRS)

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Residential proximity to commercial pesticide application has been associated with increased odds of developing chronic rhinosinusitis (CRS) with in vitro studies demonstrating cytotoxic dose‐dependent effects on sinonasal epithelia.
Melodyanne Y. Cheng   +8 more
wiley   +1 more source

Modeling Stem/Progenitor Cell-Induced Neovascularization and\ud Oxygenation around Solid Implants [PDF]

open access: yes, 2012
Tissue engineering constructs and other solid implants with biomedical applications, such as drug delivery devices or bioartificial organs, need oxygen (O2) to function properly.
Byrne, H. M.   +2 more
core  

Feeding ducks, bacterial chemotaxis, and the Gini index

open access: yes, 2015
Classic experiments on the distribution of ducks around separated food sources found consistency with the `ideal free' distribution in which the local population is proportional to the local supply rate.
Goldstein, Raymond E.   +1 more
core   +1 more source

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera   +11 more
wiley   +1 more source

Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv   +12 more
wiley   +1 more source

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