Results 131 to 140 of about 71,798 (273)
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Ryanodine receptor type 2 (RYR2) is a large calcium channel that has been identified as one of the most frequently mutated genes in lung adenocarcinoma (LUAD). Despite its potential significance, the role of RYR2 in LUAD remains poorly understood.
Tao Wang +3 more
wiley +1 more source
Cyclophilin A cooperates with MIP-2 to augment neutrophil migration
Journal of Inflammation Research, 2011 Shannon J Heine1, Denise Olive1, Ji-Liang Gao2, Philip M Murphy2, Michael I Bukrinsky1, Stephanie L Constant11Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA; 2Laboratory of Molecular ...
Heine SJ +5 more
doaj
Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far
Biotechnology and Bioengineering, EarlyView.ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor +5 more
wiley +1 more source
BMEMat, EarlyView.In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui +7 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.(1R)‐ and (1S)‐Epimers of novel isoquinoline‐derived SPMs were prepared, with a Pd‐catalyzed Heck reaction and a Ru(II)‐catalyzed asymmetric transfer hydrogenation as the key synthetic steps. Biological assessment demonstrated that several analogues significantly attenuate lipopolysaccharide‐induced NF‐κB activation and downstream pro‐inflammatory ...
Denise Moran +4 more
wiley +1 more source
Long-chain n-3 fatty acids and inflammation: potential application in surgical and trauma patients
Brazilian Journal of Medical and Biological Research, 2003 Lipids used in nutritional support of surgical or critically ill patients have been based on soybean oil, which is rich in the n-6 fatty acid linoleic acid (18:2n-6). Linoleic acid is the precursor of arachidonic acid (20:4n-6). In turn, arachidonic acid
Calder P.C.
doaj
Chemotaxis by polymorphonuclear leukocytes [PDF]
The Journal of cell biology, 1978 openaire +3 more sources
Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma
Eye &ENT Research, EarlyView.Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen +3 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Characterization of Muscle Tissue Cell Diversity and Clinical Implications in Idiopathic Inflammatory Myopathy [PDF]
Journal of CachexiaABSTRACT Background Idiopathic inflammatory myopathies (IIMs) exhibit diverse cellular microenvironments in muscle tissues, yet the full spectrum of cell populations and changes remains unclear. This study aimed to characterize cellular heterogeneity, explore cell–cell interactions and assess the prognostic value of cell subtype abundances across IIM ...
Zhu H +10 more
europepmc +2 more sources