Results 261 to 270 of about 98,425 (307)
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Assays of leukocyte locomotion and chemotaxis
Journal of Immunological Methods, 1998This review discusses the range of methods which are currently available for measuring locomotion and chemotaxis of leukocytes in vitro, their history, and some definitions of terms. Assays of the net migration of large cell populations, such as the filter assay are the most popular and are useful for identifying chemoattractant molecules, but give no ...
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Inhibition of PMN leukocytes chemotaxis by thalidomide
Archives of Dermatological Research, 1980The effects of thalidomide on chemotaxis of normal human peripheral blood PMN leukocytes have been studied in vitro. The chemotaxis factor was generated by interacting normal human serum with bovine gamma globulin-antibovine-gamma globulin immune complexes.
M, Faure, J, Thivolet, M, Gaucherand
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Molecular and Cellular Mechanisms of Leukocyte Chemotaxis
Science, 1981The application of modern scientific methods to the study of leukocyte function has begun to reveal the molecular and cytostructural bases of the chemotactic responses of these cells. Leukocyte chemotaxis is initiated by the binding of chemoattractants to distinct plasma membrane receptors; this binding alters transmembrane potential and activates ...
R, Snyderman, E J, Goetzl
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Mechanisms of leukocyte motility and chemotaxis
Current Opinion in Immunology, 1994Motility is a complex process that depends on the coordination of many cellular functions, including the conversion of information from the environment into a series of coordinated responses that culminate in directed cell movement. Major advances have been made in the understanding of many functions involved in motility, such as transmembrane ...
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Humoral Mediators of Chemotaxis of Mononuclear Leukocytes
Journal of Infectious Diseases, 1972In-vitro studies of chemotaxis of mononuclear leukocytes (MNLs) were performed to characterize humoral mediators governing the accumulation of these cells at inflammatory sites. Two humoral factors that attract MNLs in vitro were found. The first was a heat-labile factor (mol wt, 90,000) present in untreated guinea-pig serum and plasma.
M S, Hausman +2 more
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Biologic Aspects of Leukocyte Chemotaxis
1977To protect a host against microbial invasion and the development of neoplasms, the immune system must discriminate self from nonself and then efficiently localize and eliminate material recognized as nonself. The process of localizing, degrading, and eliminating nonself can be termed an immune effector function and is largely mediated by the ...
Ralph Snyderman, Marilyn Pike
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Effects of Lithium on Polymorphonuclear Leukocyte Chemotaxis
1980Lithium, known best for its efficacy in the treatment of neuropsychiatric disorders, also is capable of influencing the function of a variety of non-neural cells. Shenkman et al. (1978), for example, demonstrated that lithium was capable of enhancing several functions of human peripheral blood mononuclear cells.
H D, Perez +4 more
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Recognition of Protein Structure in Leukocyte Chemotaxis
Nature, 1973RECOGNITION of antigen in the specific immune response is well understood. Recognition of foreign or altered self material by the cells which mediate non-specific immunity has received little attention. In tissue injury or bacterial infections, many proteins may become enzymatically degraded or conformationally altered.
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Methods for Quantitation of Leukocyte Chemotaxis and Fugetaxis
2010Chemoattraction and chemorepulsion are complex directional responses of a cell to external chemotactic stimuli. The decision of a cell to move towards or away from a chemokinetic source includes detection and quantitation of the gradient of the chemotactic agent, biochemical transmission of the stimulus, and translation into a directional migration ...
VIANELLO, FABRIZIO +2 more
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