Results 241 to 250 of about 98,425 (307)

Transcriptomic profile of microglia following inflammation-sensitized hypoxic-ischemic brain injury in neonatal rats suggests strong contribution to neutrophil chemotaxis and activation. [PDF]

J Neuroinflammation
Bremer AS, Henschel N, Burkard H, Bernis ME, Ulas T, Sabir H.   +5 more
europepmc   +1 more source

Multi‐Omics Analysis in Autoimmunity: Identification of MicroRNA Regulatory Networks and Cell‐Type‐Specific Dysregulations in Multiple Sclerosis and Type 1 Diabetes

MedComm, Volume 7, Issue 4, April 2026.
This study evaluates the expression of microRNAs (miRNAs) in three distinct immune subsets (CD14+ monocytes, neutrophils, and CD8+ T cells) in multiple sclerosis and type 1 diabetes, reporting the presence of unique alteration patterns. Our integrative multi‐omics analysis suggests that miRNAs play a pivotal role in the differentiation and migration of
Jacopo Ronchi, Roberta Rigolio, Davide Maria Trevisan, Angela Papagna, Angela Stabilini, Martina Gallinaro, Maria Letizia Fusco, Martina Gaia Cogo, Guido Cavaletti, Giovanni Malerba, Manuela Battaglia, Maria Foti   +11 more
wiley   +1 more source

Exploring the shared gene signatures between rheumatoid arthritis and type 2 diabetes and their implication for drug repositioning on bioinformatics analysis. [PDF]

Medicine (Baltimore)
Qu X, Zuo X, Du H, Chen Y, Zhang Q, Peng H, Ma K, Zhang F, Cai Y, Tan L, Deng H, Chen X.   +11 more
europepmc   +1 more source

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

MedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun, Jiachen Qu, Sheng Peng, Yanan Hu, Amity Eliaz, Glenn M. Chertow, Isaac Eliaz, Zhiyong Peng   +7 more
wiley   +1 more source

Integrated transcriptomic and co-expression network analysis identifies <i>HIF1A</i> as a key immune regulator in biliary atresia. [PDF]

Transl Pediatr
Wang C, Xiong L, Li Y.
europepmc   +1 more source

Retinal Transcriptomic Signatures in Sudden Acquired Retinal Degeneration Syndrome (SARDS) and Cancer-Associated Retinopathy (CAR). [PDF]

Animals (Basel)
Grozdanic S, Poleksic A, Racic D, Bock D, Lazic T, Kuehn M.   +5 more
europepmc   +1 more source

Methionine and choline deficiency rewires transcriptional programs to recapitulate molecular features of human MASH. [PDF]

J Lipid Res
You W, Ji J, Nguyen N, Esp L, Sun X.
europepmc   +1 more source

Neutrophils at the Crossroads of Oral Microbiome Dysbiosis and Periodontal Disease. [PDF]

Microorganisms
Viana J, Ferro T, Pitschieller R, Machado V, Su N, Mendes JJ, Botelho J.   +6 more
europepmc   +1 more source

The Myeloid Biomarker <i>MS4A6A</i> Drives an Immunosuppressive Microenvironment in Glioblastoma via Activation of the PGE2 Signaling Axis. [PDF]

Int J Mol Sci
Chen J, Wu Q, Berglund AE, Macaulay RJ, Mulé JJ, Etame AB.   +5 more
europepmc   +1 more source