Results 251 to 260 of about 98,425 (307)
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Assays of Leukocyte Chemotaxis
Annual Review of Medicine, 1986A number of disorders of leukocyte motility and chemotaxis have been reported clinically. In this paper we present a rational approach for testing cell populations for a defect in leukocyte migration and for defining the cellular basis of any abnormality observed. The principles and difficulties of individual and population-type assays are discussed.
S H, Zigmond, D A, Lauffenburger
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Disorders of Leukocyte Chemotaxis
Pediatric Clinics of North America, 1977The rapid accumulation of inflammatory cells at sites of microbial invasion or neoplastic transformation is a central event in immunologically-mediated host defense. The availability of methodology to accurately quantify leukocyte migration in vitro has allowed the disclosure of previously unrecognized clinical disorders, namely leukocyte dysmotility ...
R, Snyderman, M C, Pike
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Leukocyte Chemotaxis and Pyoderma Gangrenosum
International Journal of Dermatology, 1985Abstract: Leukocyte chemotaxis (in five patient with pyoderma gangrenosum) was studied using a modification of the Boyden chamber method. In all patients the chemotactic response was significantly lower than in the controls. This abnormal chemotaxis was a result of an intrinsic neutrophil dysfunction. No significant difference was detected between the
P. Nerella +3 more
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Chemotaxis of nurse shark leukocytes
Developmental & Comparative Immunology, 1985Studies were conducted to determine the ability of leukocytes from the nurse shark to migrate in an in vitro micropore filter chemotaxis assay and to determine optimal assay conditions and suitable attractants for such an assay. A migratory response was seen with several attractants: activated rat serum, activated shark plasma, and a pool of shark ...
S D, Obenauf, S H, Smith
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Polymorphonuclear leukocyte chemotaxis in sporotrichosis
Mycopathologia, 1982A lesion of sporotrichosis shows a characteristic arrangement of the infiltrate in three zones: the central suppurative zone composed of polymorphonuclear leukocytes, the tuberculoid zone and the round cell zone. For investigating the pathomechanism of the suppurative zone formation, polymorphonuclear leukocyte chemotaxis to sporotrichin was assayed ...
H, Hachisuka +3 more
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Protein methylesterase and leukocyte chemotaxis
Molecular Immunology, 1980Abstract The involvement of protein carboxylmethylesterase in leukotaxis has been studied. The enzyme is localized in the cytosolic fraction of neutrophils. In intact cells the presence of a chemoattractant induces a rapid stimulation of enzymatic activity. An half-maximal stimulation of this activity is induced by a concentration (3 n M ) of peptide
K, Venkatasubramanian +6 more
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Chemotaxis of polymorphonuclear leukocytes
Biochemical Pharmacology, 1968Abstract Chemotaxis of polymorphonuclear leukocytes (PMN) has been studied by the use of chambers with micropore filters. This technique measures the specific, unidirectional migration of PMN toward an attractant. The nature of the medium in which the cells are suspended is important because homologous serum considerably increases cell responsiveness
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Cellular augmentation of polymorphonuclear leukocyte chemotaxis
American Journal of Physiology-Cell Physiology, 1979The density of neutrophils influences the number of cells that will respond to a chemoattractant, endotoxin-activated serium. When fewer than 3 x 10(5) polymorphonuclear leukocytes (PMN) were placed in the top compartment of a modified Boyden chemotaxis chamber, the cellular response was weak.
A, Takeuchi, R H, Persellin
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