Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years
Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay +2 more
wiley +1 more source
Distinct PlzC mechanisms integrate chemotaxis and c-di-GMP signaling to regulate <i>Vibrio cholerae</i> motility and biofilm formation. [PDF]
Park JH +6 more
europepmc +1 more source
Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley +1 more source
A 3D model to evaluate cell chemotaxis within a heterogenic tumor microenvironment.
Rodrigues DB +6 more
europepmc +1 more source
Related Dictyostelium G protein subunits Gα1 and Gα2 have different roles in chemotaxis and transcription factor regulation. [PDF]
Kiger NM +3 more
europepmc +1 more source
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
A 3D-printed capillary tube holder for high-throughput chemotaxis assays. [PDF]
Berruto C +3 more
europepmc +1 more source
The multiple hit model of infantile and epileptic spasms: The 2025 update
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Wormtrails: a python package for viewing <i>C. elegans</i> movement. [PDF]
Ashih CD, Xu Y, Apfeld J.
europepmc +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source

