Results 191 to 200 of about 260,357 (315)

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Suppression of Leukocyte Chemotaxis in vitro by Chemotherapeutic Agents Used in the Management of Thermal Injuries

, 1975
Glenn D. Warden, Arthur D. Mason, Basil A. Pruitt   +2 more
openalex   +2 more sources

Abnormal polymorphonuclear leucocyte chemotaxis in Behcet's syndrome. [PDF]

, 1979
D W James, John R. Walker, M. J. H. Smith   +2 more
openalex   +1 more source

Translation of a Human‐Based Malaria‐on‐a‐Chip Phenotypic Disease Model for In Vivo Applications

Advanced Science, EarlyView.
Inoculation of the Malaria‐on‐a‐Chip model with human erythrocytes infected with Plasmodium falciparum can support the entire intraerythrocytic lifecycle for 7 days in vitro. Utilizing this human‐based, serum‐free model provides an alternative to animal testing by introducing a human‐based, preclinical alternative for antimalarial therapeutic delivery.
Michael J. Rupar, Hannah M. Hanson, Brianna L. Botlick, Narasimhan Sriram, Stephanie Rogers, Justin Zuniga, Zhanhe Liu, Steven J. Trimmer, Joseph M. Ciurca, Christopher J. Long, Christopher W. McAleer, Stephan Schmidt, Paola Favuzza, Philip Lowe, Nathalie Gobeau, James J. Hickman   +15 more
wiley   +1 more source

Dissection of Behavioral Components and the Role of Omega/Delta Turns for the Chemotaxis of C. elegans. [PDF]

Genes Cells
Suwazono K, Kuze K, Tazawa UT, Jang MS, Kunitomo H, Toyoshima Y, Iino Y.   +6 more
europepmc   +1 more source

EFFECTS OF INDUCTION AGENTS AND NON VOLATILE ANESTHETICS ON CHEMOTAXIS OF POLY_MORPHONUCLEAR LEUKOCYTES (PMN) [PDF]

, 1979
A. Mathieu, Diana Mathieu, N.E. Hyslop
openalex   +1 more source

Targeting eRNA‐Producing Super‐Enhancers Regulates TNFα Expression and Mitigates Chronic Inflammation in Mice and Patient‐Derived Immune Cells

Advanced Science, EarlyView.
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho, Su Min Kim, Jiyeon Lee, Oh Chan Kwon, Wonjin Woo, Eunji Lee, Hyo Jin Park, Yeongun Lee, So Hee Dho, Tae‐Kyung Kim, Min‐Chan Park, Richard A. Flavell, Lark Kyun Kim   +12 more
wiley   +1 more source

A Method for Measuring Chemotaxis and Use of the Method to Determine Optimum Conditions for Chemotaxis by Escherichia coli

, 1973
Julius Adler
openalex   +1 more source

YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis

Advanced Science, EarlyView.
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li, Xueying Li, Chunhong Liu, Zhenzhi Li, Kaixin Ding, Yuxin Wang, Ning Gu, Liwei Xie, Zheng Chen   +8 more
wiley   +1 more source

Identification of a gamma-glutamyl methyl ester in bacterial membrane protein involved in chemotaxis.

, 1977
Paul van der Werf, Daniel E. Koshland
openalex   +1 more source