The Carboxyl Tail of Protease-activated Receptor-1 Is Required for Chemotaxis
Gilberto R. Sambrano, Shaun R. Coughlin
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Extramedullary Disease—Achilles Heel in Myeloma?
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar +7 more
wiley +1 more source
P2Y14 receptor activation and neutrophil signaling: linking inflammation to systemic pathophysiology. [PDF]
da Silva Ebone R +4 more
europepmc +1 more source
Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville +6 more
wiley +1 more source
Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis. [PDF]
Wang T +17 more
europepmc +1 more source
Global solutions to a two-species chemotaxis system with gradient dependent sensitivity
Changchun Liu, Enhui Pan
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This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Effects of MAPK Homologous Genes on Chemotaxis and Egg Hatching in <i>Meloidogyne incognita</i>. [PDF]
Wang Y, Liu M, Li J, Hu C, Liu Y.
europepmc +1 more source
A 3D model to evaluate cell chemotaxis within a heterogenic tumor microenvironment.
Rodrigues DB +6 more
europepmc +1 more source
Teaching the laboratory assessment of neutrophil chemotaxis: a simulation-based approach for undergraduate immunology. [PDF]
Costabile M, Denyer G.
europepmc +1 more source

