Results 231 to 240 of about 277,006 (294)

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Specificities of chemosensory receptors in the human gut microbiota. [PDF]

Proc Natl Acad Sci U S A
Xu W, Jalomo-Khayrova E, Gumerov VM, Ross PA, Köbel TS, Schindler D, Bange G, Zhulin IB, Sourjik V.   +8 more
europepmc   +1 more source

Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure – interaction between loss of Y chromosome and clonal haematopoiesis

European Journal of Heart Failure, EarlyView.
Abstract Aims Age‐associated clonal haematopoiesis of indeterminate potential (CHIP) has been linked to increased incidence and worse prognosis of chronic heart failure (CHF). CHIP arises from somatic mutations in haematopoietic stem and progenitor cells. Mosaic loss of Y chromosome (LOY), the most common somatic mutation in male blood cells, increases
Sebastian Cremer, Moritz von Scheidt, Klara Kirschbaum, Lukas Tombor, Silvia Mas‐Peiro, Wesley Abplanalp, Tina Rasper, Akshay Ware, Andrin Schuff, Alexander Berkowitsch, Johannes Krefting, David Leistner, Heribert Schunkert, Thimoteus Speer, Stefanie Dimmeler, Andreas Michael Zeiher   +15 more
wiley   +1 more source

The role of contact guidance and ECM remodelling in cancer invasion: a computational study

Botticelli M, Metzcar J, Macklin P, Keshavanarayana P, Spill F.   +4 more
europepmc   +1 more source

Pregnancy exacerbates neutrophil responses in murine lungs and alters gut microbiota composition after cigarette smoke exposure. [PDF]

Front Immunol
Dehghani A, Wang L, Garssen J, Styla E, Leusink-Muis T, van Ark I, Folkerts G, van Bergenhenegouwen J, Braber S.   +8 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Highly Selective Exogenous Neutrophils Effectively Inhibit Growth of Colon Cancer under the Guidance of Precision Navigation. [PDF]

Research (Wash D C)
Yang Y, Li C, Shao Y, Wen X, Lu C, Gao X, Mei Y, Sun B.   +7 more
europepmc   +1 more source

Target Binding of Black Phosphorus Nanomaterial to Polo‐Like Kinase 1 for Cancer Chemotherapy: A Mutual Selection of Nanomaterial and Protein

Exploration, EarlyView.
This study investigates the effect of protein properties on the nanomaterial‐protein interaction and elucidates the molecular mechanisms underlying the targeted inhibition of polo‐like kinase (PLK1) by black phosphorus nanomaterials (BPNMs). The specific targeting inhibition is attributed to the intrinsic properties of both the PLK1 protein and the ...
Fangfang Liu, Zhong‐Da Li, Yanqiao Zeng, Xiaofeng Wang, Yingnan Liu, Qi Li, Wenhe Luo, Xiaoman Suo, Yaqing Xu, Feng Yuan, Dan Zhang, Wuqiong Zhang, Shengyong Geng, Xue‐Feng Yu, Guofang Zhang, Yang Li   +15 more
wiley   +1 more source

Photodegradable Hydrogel Matrices for Spatiotemporal Control of Bacteria Transport and Delivery. [PDF]

ACS Appl Mater Interfaces
Reed JA, Retterer ST, Hansen RR.
europepmc   +1 more source