Results 21 to 30 of about 276,157 (197)

Different migration patterns of sea urchin and mouse sperm revealed by a microfluidic chemotaxis device. [PDF]

PLoS ONE, 2013
Chemotaxis refers to a process whereby cells move up or down a chemical gradient. Sperm chemotaxis is known to be a strategy exploited by marine invertebrates such as sea urchins to reach eggs efficiently in moving water.
Haixin Chang, Beum Jun Kim, Yoon Soo Kim, Susan S Suarez, Mingming Wu   +4 more
doaj   +1 more source

Mechanisms involved in human eosinophil chemotaxis induced by the newly cloned C-C chemokine eotaxin

Allergology International, 1998
The present study was performed in order to investigate the mechanism(s) involved in eotaxin-induced normal human eosinophil chemotaxis using a 48-well micro-chemotaxis chamber assay.
Amr El-Shazly, Keisuke Masuyama, Masao Eura, Takeru Ishikawa   +3 more
doaj   +1 more source

Enhancer of zeste homolog 2 enhances the migration and chemotaxis of dental mesenchymal stem cells

Journal of International Medical Research, 2020
Objective To investigate the function of enhancer of zeste homolog 2 (EZH2) in the migration and chemotaxis of human dental tissue-derived mesenchymal stem cells. Methods The expression of EZH2, C-X-C motif chemokine ligand 11 (CXCL11), CXCL16, and CXCR1
Huarui Ma, Shaoyu Duan, Fei Yan, Haoqing Yang, Yangyang Cao, Lihua Ge, Runtao Gao   +6 more
doaj   +1 more source

Identification of Positive Chemotaxis in the Protozoan Pathogen Trypanosoma brucei

mSphere, 2020
To complete its infectious cycle, the protozoan parasite Trypanosoma brucei must navigate through diverse tissue environments in both its tsetse fly and mammalian hosts. This is hypothesized to be driven by yet unidentified chemotactic cues.
Stephanie F. DeMarco, Edwin A. Saada, Miguel A. Lopez, Kent L. Hill   +3 more
doaj   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Counterclockwise rotation of the flagellum promotes biofilm initiation in Helicobacter pylori

mBio
Motility promotes biofilm initiation during the early steps of this process: microbial surface association and attachment. Motility is controlled in part by chemotaxis signaling, so it seems reasonable that chemotaxis may also affect biofilm formation ...
Xiaolin Liu, Paphavee Lertsethtakarn, Vanessa T. Mariscal, Fitnat Yildiz, Karen M. Ottemann   +4 more
doaj   +1 more source

Singly Flagellated Pseudomonas aeruginosa Chemotaxes Efficiently by Unbiased Motor Regulation

mBio, 2016
Pseudomonas aeruginosa is an opportunistic human pathogen that has long been known to chemotax. More recently, it has been established that chemotaxis is an important factor in the ability of P. aeruginosa to make biofilms. Genes that allow P. aeruginosa
Qiuxian Cai, Zhaojun Li, Qi Ouyang, Chunxiong Luo, Vernita D. Gordon   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Asymmetric random walks reveal that the chemotaxis network modulates flagellar rotational bias in Helicobacter pylori

eLife, 2021
The canonical chemotaxis network modulates the bias for a particular direction of rotation in the bacterial flagellar motor to help the cell migrate toward favorable chemical environments.
Jyot D Antani, Anita X Sumali, Tanmay P Lele, Pushkar P Lele   +3 more
doaj   +1 more source