Results 31 to 40 of about 320,850 (300)

TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide

open access: yesScientific Reports, 2021
Neutrophils must navigate accurately towards pathogens in order to destroy invaders and thus defend our bodies against infection. Here we show that hydrogen peroxide, a potent neutrophil chemoattractant, guides chemotaxis by activating calcium-permeable ...
Hassan Morad   +4 more
doaj   +1 more source

Quantitative Analysis of Cell Motility and Chemotaxis in Dictyostelium discoideum by Using an Image Processing System and a Novel Chemotaxis Chamber Providing Stationary Chemical Gradients [PDF]

open access: yes, 1989
An image processing system was programmed to automatically track and digitize the movement of amebae under phase-contrast microscopy. The amebae moved in a novel chemotaxis chamber designed to provide stable linear attractant gradients in a thin agarose ...
G Gerisch   +5 more
core   +1 more source

Drug targeting to decrease cardiotoxicity – determination of the cytotoxic effect of GnRH-based conjugates containing doxorubicin, daunorubicin and methotrexate on human cardiomyocytes and endothelial cells

open access: yesBeilstein Journal of Organic Chemistry, 2018
Background: Cardiomyopathy induced by the chemotherapeutic agents doxorubicin and daunorubicin is a major limiting factor for their application in cancer therapy.
Livia Polgár   +7 more
doaj   +1 more source

Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo

open access: yesJournal of Lipid Research, 2013
Monocyte chemoattractant protein-1 (MCP-1)-induced monocyte chemotaxis is a major event in inflammatory disease. Our prior studies have demonstrated that MCP-1-dependent chemotaxis requires release of arachidonic acid (AA) by activated cytosolic ...
Suman Kundu   +8 more
doaj   +1 more source

Chemotaxis- and locomotion-test plates.

open access: yes, 2023
(A) Schematic of a chemotaxis-test plate used for chemotaxis assays, except for tracking analyses of worm locomotion. Fifteen to two hundred worms were used in each assay.
Keita Katae (16940897)   +7 more
core   +1 more source

Chemotactic network responses to live bacteria show independence of phagocytosis from chemoreceptor sensing

open access: yeseLife, 2017
Aspects of innate immunity derive from characteristics inherent to phagocytes, including chemotaxis toward and engulfment of unicellular organisms or cell debris.
Netra Pal Meena, Alan R Kimmel
doaj   +1 more source

A new class of protein sensor links spirochete pleomorphism, persistence, and chemotaxis

open access: yesmBio, 2023
Pathogenic spirochetes can alter their morphologies and behaviors to infect and survive within their hosts. Previous reports demonstrate that the formation of the so-called “round bodies” and biofilms, and chemotaxis are involved in spirochete ...
A. R. Muok   +7 more
doaj   +1 more source

The Novel Protein Cj0371 Inhibits Chemotaxis of Campylobacter jejuni

open access: yesFrontiers in Microbiology, 2018
cj0371 is a novel gene that is associated with Campylobacter jejuni virulence, and an isogenic mutant of cj0371 showed hyper chemotaxis and motility. Chemotactic motility is an important virulence factor and is involved in C.
Xueqing Du   +5 more
doaj   +1 more source

THE CHEMOSUPPRESSION OF CHEMOTAXIS [PDF]

open access: yesThe Journal of Experimental Medicine, 1966
The effects of various drugs on chemotaxis of polymorphonuclear leukocytes (PMN's) in vitro and in vivo have been studied. Response of rabbit PMN's in vitro to the chemotactic factor of rabbit serum, consisting of an activated protein-protein complex of the fifth and sixth (and probably seventh) components of complement (C'), is suppressed by ...
openaire   +2 more sources

Software: An automated approach to quantify chemotaxis index in C. elegans

open access: yes, 2022
A command-line interface to measure chemotaxis index (CI) from chemotaxis assay imagesRelated ...
Timothy A Crombie
core   +1 more source

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