Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. [PDF]
The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potential.
Gabriela Kalna (192504) +76 more
core +1 more source
Preprint: Artemisinin inhibits innate immune cell chemotaxis, cytokine production and NET release
Immune cell chemotaxis to the sites of pathogen invasion is critical for fighting infection, but in life-threatening conditions such as sepsis and Covid-19, excess activation of the innate immune system is thought to cause a damaging invasion of immune ...
Vilar, B. +7 more
core +1 more source
A minimal model of metabolism-based chemotaxis. [PDF]
Since the pioneering work by Julius Adler in the 1960's, bacterial chemotaxis has been predominantly studied as metabolism-independent. All available simulation models of bacterial chemotaxis endorse this assumption.
Matthew D Egbert +2 more
doaj +1 more source
Chemotaxis-based smart drug delivery of epirubicin using a 3D printed microfluidic chip
Chemotaxis-based smart drug delivery of epirubicin using a 3D printed microfluidic ...
K Dalvand (16254908) +3 more
core +1 more source
Feedback Control Architecture and the Bacterial Chemotaxis Network
This paper investigates the chemotaxis behavior of the bacterium R. sphaeroides. We review the results of a recent study comparing different possible mathematical models of this bacterium's chemotaxis decision mechanisms.
Mark A J Roberts +34 more
core +1 more source
Different migration patterns of sea urchin and mouse sperm revealed by a microfluidic chemotaxis device. [PDF]
Chemotaxis refers to a process whereby cells move up or down a chemical gradient. Sperm chemotaxis is known to be a strategy exploited by marine invertebrates such as sea urchins to reach eggs efficiently in moving water.
Haixin Chang +4 more
doaj +1 more source
Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK/ERK signaling [PDF]
Background: Morus alba has long been used in traditional Chinese medicine to treat inflammatory diseases;however, the scientific basis for such usage and the mechanism of action are not well understood. This studyinvestigated the action of M.
Yin-Jing Tien +9 more
core +1 more source
THE CHEMOSUPPRESSION OF CHEMOTAXIS [PDF]
The effects of various drugs on chemotaxis of polymorphonuclear leukocytes (PMN's) in vitro and in vivo have been studied. Response of rabbit PMN's in vitro to the chemotactic factor of rabbit serum, consisting of an activated protein-protein complex of the fifth and sixth (and probably seventh) components of complement (C'), is suppressed by ...
openaire +2 more sources
Mechanisms involved in human eosinophil chemotaxis induced by the newly cloned C-C chemokine eotaxin
The present study was performed in order to investigate the mechanism(s) involved in eotaxin-induced normal human eosinophil chemotaxis using a 48-well micro-chemotaxis chamber assay.
Amr El-Shazly +3 more
doaj +1 more source
An image processing system was programmed to automatically track and digitize the movement of amebae under phase-contrast microscopy. The amebae moved in a novel chemotaxis chamber designed to provide stable linear attractant gradients in a thin agarose ...
G Gerisch +5 more
core +1 more source

