Results 31 to 40 of about 212,420 (268)

Quality of life changes during adjuvant chemotherapy in patients with colon cancer [PDF]

open access: yesKorean Journal of Clinical Oncology, 2016
Purpose: The survival of advanced colon cancer patients has increased due to the development of surgical techniques and adjuvant chemotherapy. The administration of adjuvant chemotherapy after curative resection is generally accepted as a standard of ...
Seo Hee Lee   +5 more
doaj   +1 more source

A regression framework for a probabilistic measure of cost-effectiveness [PDF]

open access: yesarXiv, 2021
To make informed health policy decisions regarding a treatment, we must consider both its cost and its clinical effectiveness. In past work, we introduced the net benefit separation (NBS) as a novel measure of cost-effectiveness. The NBS is a probabilistic measure that characterizes the extent to which a treated patient will be more likely to ...
arxiv  

The impact of Oncotype DX testing on adjuvant chemotherapy decision making in 1–3 node positive breast cancer

open access: yesCancer Reports, 2022
Background Oncotype DX testing has reduced the use of adjuvant chemotherapy in node‐negative early breast cancer but less is known about its impact in node positive patients.
Yogeshkumar Malam   +5 more
doaj   +1 more source

Mathematical modeling of glioma invasion and therapy approaches via kinetic theory of active particles [PDF]

open access: yesarXiv, 2022
A multiscale model for glioma spread in brain tissue under the influence of vascularization and vascular endothelial growth factors is proposed. It accounts for the interplay between the different components of the neoplasm and the healthy tissue and it investigates and compares various therapy approaches.
arxiv  

Neo-adjuvant and adjuvant chemotherapy in bladder cancer

open access: yesAnnals of Oncology, 2007
Transitional cell carcinoma of the bladder represents the second most common genitourinary malignancy [1]; the clinical approach to muscle-invasive disease has been modified in the last decade, considering the important role of multidisciplinary team, including surgeon, oncologist and radiotherapist.
D'AURIA, GIULIANA   +6 more
openaire   +3 more sources

The practical roadmap for peri-cystectomy approaches in muscle-invasive bladder cancer

open access: yesFrontiers in Oncology
The management of muscle-invasive bladder cancer (MIBC) remains a challenging topic since it is witnessing rapidly evolving changes and new drug approvals. In fact, more effective approaches are now available to improve the outcomes of patients with MIBC
Joseph Kattan   +3 more
doaj   +1 more source

Adjuvant chemotherapy in node‐positive patients after esophagectomy for esophageal squamous cell carcinoma

open access: yesThoracic Cancer, 2023
Background The role of adjuvant chemotherapy in esophageal squamous cell carcinoma (ESCC) remains controversial. This study aimed to evaluate the impact of adjuvant chemotherapy on survival in patients with positive nodes after surgery for ESCC.
Yeong Jeong Jeon   +5 more
doaj   +1 more source

Making accurate and interpretable treatment decisions for binary outcomes [PDF]

open access: yesarXiv, 2023
Optimal treatment rules can improve health outcomes on average by assigning a treatment associated with the most desirable outcome to each individual. Due to an unknown data generation mechanism, it is appealing to use flexible models to estimate these rules. However, such models often lead to complex and uninterpretable rules.
arxiv  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

A phase II study of neoadjuvant capecitabine, oxaliplatin, and irinotecan (XELOXIRI) in patients with locally advanced rectal cancer

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 81-90, January 2023., 2023
XELOXIRI neoadjuvant chemotherapy appears to be feasible and efficacious for patients with LARC. Although neoadjuvant XELOXIRI alone did not yield our expected pCR rate, the local recurrence rate, 3‐year DFS and measures of safety met current standards.
Chu Matsuda   +16 more
wiley   +1 more source

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