Results 51 to 60 of about 60,074 (286)

Risk factors associated with antineoplastic chemotherapy-induced nausea and vomiting

Revista de Saúde Pública, 2020
OBJECTIVE: To estimate the incidence and to evaluate risk factors for antineoplastic nausea and vomiting with high and moderate emetogenic chemotherapy in adult patients in the first treatment cycle.
Giovana Paula Rezende Simino, Ilka Afonso Reis, Francisco de Assis Acurcio, Eli Iola Gurgel Andrade, Natalia Maria Linhares Brazil, Mariângela Leal Cherchiglia   +5 more
doaj   +2 more sources

D2 Receptors and Sodium Ion Channel Blockades of the Basolateral Amygdala Attenuate Lithium Chloride-Induced Conditioned Taste Aversion Applying to Cancer Chemotherapy Nausea and Vomiting

Brain Sciences, 2023
Cancer patients regularly suffer from the behavioral symptoms of chemotherapy-induced nausea and vomiting. Particularly, it is involved in Pavlovian conditioning. Lithium chloride (LiCl) was used as the unconditioned stimulus (US) and contingent with the
Zhi-Yue Gao, Chung Ming Huang, Cai-N Cheng, Andrew Chih-Wei Huang   +3 more
doaj   +1 more source

Anti-emetic effects of thalidomide: Evidence, mechanism of action, and future directions

Current Research in Pharmacology and Drug Discovery, 2022
The rationale for using thalidomide (THD) as a treatment for nausea and vomiting during pregnancy in the late 1950s appears to have been based on its sedative or hypnotic properties.
Paul L.R. Andrews, Robin S.B. Williams, Gareth J. Sanger   +2 more
doaj   +1 more source

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting. [PDF]

, 2015
PurposeTo determine the incidence of chemotherapy-induced nausea/vomiting (CINV) and chemotherapy treatment delay and adherence among patients receiving palonosetron versus other 5-hydroxytryptamine receptor antagonist (5-HT3 RA) antiemetics.Materials ...
Grabner, Michael, Palli, Swetha Rao, Quimbo, Ralph A, Rugo, Hope S   +3 more
core   +2 more sources

Impact of Nausea and Vomiting on Quality of Life in Cancer Patients During Chemotherapy

Health and Quality of Life Outcomes, 2003
It is commonly claimed that the nausea and vomiting accompanying cytotoxic chemotherapy have a negative impact on health-related quality of life. While this may seem self-evident, until a few years ago there was little empirical data demonstrating that ...
Roila Fausto, Ballatori Enzo
doaj   +1 more source

Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting [PDF]

, 2016
BACKGROUND We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy.
Bajaj, Madhuri, Biggs, David, Dietrich, Leah, Lafky, Jacqueline M., Liu, Heshan, Loprinzi, Charles L., Navari, Rudolph M., Powell, Steven F., Qin, Rui, Ruddy, Kathryn J.   +9 more
core   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study [PDF]

, 2017
Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change
A Freeman, A Tidholm, AM Holmes, B Otto, C Pirri, C Rojas, CC Horn, CC Horn, CJ Henry, DB Smith, DB Zamble, DG Warr, F Roila, F Roila, FD Tattersall, GJ Sanger, GJ Sanger, GR Morrow, H Fukui, H Fukui, H Kenward, H Kenward, Hannah Kenward, JA Gylys, JA Rudd, Jonathan Elliott, K Olsson, Ludovic Pelligand, LX Cubeddu, M Marty, M Mutoh, N Percie du Sert, N Percie du Sert, PH Mulder De, PJ Hesketh, PJ Hesketh, PL Andrews, RJ Gralla, RM Stern, RM Stern, S Kretzing, S Poli-Bigelli, SG Allan, SP Chawla, Terry Lee, TM Hyde, V Napadow, VA Puente-Redondo de la   +47 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Management of chemotherapy-induced nausea and vomiting

Indian Pediatrics, 2010
Chemotherapy-induced nausea and vomiting (CINV) is a significant problem in the treatment of children with cancer. The last decade has seen a variety of newer antiemetics being evaluated for CINV; their efficacy and side effects need to be assessed in children.
Pooja, Dewan, Swati, Singhal, Deepika, Harit   +2 more
openaire   +4 more sources