Results 81 to 90 of about 60,074 (286)

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

Olanzapine enhances the effect of conventional drugs in chemotherapy induced nausea and vomiting: A randomized clinical trial

Caspian Journal of Internal Medicine, 2022
Background: Chemotherapy inducing nausea and vomiting (CINV) is one of the significant   side  effects of anti-cancer treatment, and its full prevention is a potential challenge.
Atefe Khani, Ali Eishy Oskuyi, Rahim Asghari, Hamid Reza Khalkhali, Hamdollah Sharifi   +4 more
doaj  

Interventions for preventing oral mucositis for patients with cancer receiving treatment [PDF]

, 2003
Background: Treatment of cancer with chemotherapy is becoming increasingly more effective but is associated with short and long-term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them ...
Bryan, Gemma, Clarkson, Jan E., Furness, Susan, Glenny, Anne-Marie, Khalid, Tasneem, Littlewood, Anne, McCabe, Martin G., Meyer, Stefan, Worthington, Helen V.   +8 more
core   +3 more sources

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Efficacy of ginger (Zingiber officinale) in ameliorating chemotherapy-induced nausea and vomiting and chemotherapy-related outcomes: a systematic review update and meta-analysis [PDF]

, 2019
Background: Ginger has been proposed as an adjuvant treatment for chemotherapy-induced nausea and vomiting. Objective: The aim of this systematic review with meta-analyses is to evaluate, in adult cancer patients receiving chemotherapy, the effects of ...
Crichton, Megan, Isenring, Elisabeth, Marshall, Skye, Marx, Wolfgang, McCarthy, Alexandra L.   +4 more
core   +1 more source

Gastrointestinal manifestations following chimeric antigen receptor T‐cell (CAR‐T) 19 therapy in pediatric patients with CD19+ acute lymphoblastic leukemia

JPGN Reports, EarlyView.
Abstract Pediatric patients with CD19+ acute lymphoblastic leukemia (ALL) undergoing chimeric antigen receptor T‐cell (CAR‐T) therapy frequently experience gastrointestinal (GI) complications. A retrospective study analyzed 13 patients (median age: 8 years) treated between January 2020 and January 2024.
Judith Raya Muñoz, Melissa Panesso Romero, Saray Mesonero Cavia, Marta Freixas Bermejo, Vanessa Cabello Ruiz, Marina Álvarez Beltran, Maria Cristina Díaz de Heredia Rubio, Susana Elena Redecillas Ferreiro, Oscar Segarra Canton   +8 more
wiley   +1 more source

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin, Ming‐Lun Yeh, Po‐Cheng Liang, Shinn‐Cherng Chen, Chung‐Feng Huang, Jee‐Fu Huang, Chia‐Yen Dai, Ming‐Lung Yu, Wan‐Long Chuang   +8 more
wiley   +1 more source

Reappraisal of the role of dolasetron in prevention and treatment of nausea and vomiting associated with surgery or chemotherapy

Cancer Management and Research, 2012
S Michael Roberts, Dmitri S Bezinover, Piotr K JanickiDepartment of Anesthesiology, Penn State College of Medicine, Penn State Milton S Hershey Medical Center, Hershey, PA, USAAbstract: Chemotherapy-induced nausea and vomiting and postoperative nausea ...
Janicki PK, Bezinover DS, Roberts SM
doaj  

Neuromotor tolerability and behavioural characterisation of cannabidiolic acid, a phytocannabinoid with therapeutic potential for anticipatory nausea [PDF]

, 2016
Rationale: Anticipatory nausea (AN) is a poorly controlled side-effect experienced by chemotherapy patients. Currently, pharmacotherapy is restricted to benzodiazepine anxiolytics, which have limited efficacy, significant sedative effects, and induce ...
A Rex, AC Campos, AJ Hill, ARM Schier de, Benjamin J Whalley, C Figueroa-Moseley, C Gross, C Kamen, C Kilkenny, C Sánchez, Claire M Williams, CM Williams, CM Williams, D Bolognini, D Campos, D Razavi, Daniel I Brierley, DH Bovbjerg, DR Britton, E Basch, E Rock, EM Rock, EM Rock, EM Rock, F Roila, G Griebel, G Griebel, IA Malik, J Zhang, JA Farrimond, JA Farrimond, JA Farrimond, JA Farrimond, JA Roscoe, James Samuels, JC McGrath, JD Hainsworth, JL Stanley, JT Hickok, K Ahlberg, K Lotfi-Jam, L Prut, LV Santos Dos, M Bourin, M Martin, Marnie Duncan, MC Janelsins, MG Kris, N Stephens, NL Cluny, OA Meyer, P Curzon, PJ Hesketh, PJ Hesketh, RM Navari, RM Nesse, S Matteson, SA Ferguson, SC Dulawa, TDM Hill, V Duvvuri   +60 more
core   +1 more source

Economic evaluation of ondansetron: Preliminary analysis using clinical trial data prior to price setting [PDF]

, 1992
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright © 1992 Macmillan Press Ltd.This study combines secondary analysis of efficacy and side-effect data from a randomised ...
Buxton, MJ, O'Brien, BJ
core   +1 more source