Results 21 to 30 of about 28,175 (193)

Optimal management of chemotherapy-induced thrombocytopenia with thrombopoietin receptor agonists. [PDF]

Blood Rev
Chemotherapy-induced thrombocytopenia (CIT) is a common complication of antineoplastic therapy, resulting in antineoplastic therapy dose reductions, treatment delays, treatment discontinuation, and morbid bleeding events. Despite several decades of research into thrombopoietic growth factors in CIT, there are presently no available U.S.
Al-Samkari H.
europepmc   +3 more sources

Effects of quercetin and extracts from Phyllanthus emblica, Morus alba, and Ginkgo biloba on platelet recovery in a rat model of chemotherapy-induced thrombocytopenia [PDF]

Heliyon
Background: Chemotherapy-induced thrombocytopenia (CIT) is a major reason for chemotherapy delays, dose reduction, or even treatment discontinuation, which may impact oncologic outcomes.
Kriangkrai Chawansuntati, Sayamon Hongjaisee, Kittichai Sirita, Kornkamon Kingkaew, Kritsadee Rattanathammethee, Benjawan Kumrapich, Sakaewan Ounjaijean, Aphisek Kongkaew, Nongkran Lumjuan   +8 more
doaj   +2 more sources

Evaluation of the Efficacy of Romiplostim in Management of Chemotherapy-Induced Thrombocytopenia in Indian Patients: A Retrospective Study [PDF]

South Asian Journal of Cancer
Vikas Talreja, Sangeeta Khatwani, Priyanka Subhagan   +2 more
doaj   +2 more sources

Efficacy and safety of different treatments in chemotherapy-induced thrombocytopenia: a systematic review and network meta-analysis [PDF]

Frontiers in Pharmacology
Wu Xuedong, Ruan Yongsheng, Xu Xiaoxiao   +2 more
exaly   +2 more sources

Efficacy of Carica Papaya Leaf Extract in Reducing Treatment-Delay Secondary to Chemotherapy induced Thrombocytopenia [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Chemotherapy Induced Thrombocytopenia (CIT) is a common problem in clinical oncology. It leads to delay in administration of chemotherapy resulting in inferior outcomes.
Priyanka Sreelatha, Wesley Mannirathil Jose   +1 more
doaj   +1 more source

Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin

Pharmacological Research, 2022
Thrombocytopenia, a most common complication of radiotherapy and chemotherapy, is an important cause of morbidity and mortality in cancer patients. However, there are still no approved agents for the treatment of radiation- and chemotherapy-induced ...
Long Wang, Ting Zhang, Sha Liu, Qi Mo, Nan Jiang, Qi Chen, Jing Yang, Yun-Wei Han, Jian-Ping Chen, Fei-Hong Huang, Hua Li, Jie Zhou, Jie-Si Luo, Jian-Ming Wu   +13 more
doaj   +1 more source

Fibrinolysis in patients with chemotherapy‐induced thrombocytopenia and the effect of platelet transfusion [PDF]

Journal of Thrombosis and Haemostasis, 2019
Essentials Bleeding in chemotherapy induced thrombocytopenia (CIT) might be influenced by hyperfibrinolysis. t-PA-thromboelastography is a fast and reliable assay for hyperfibrinolysis in CIT patients. Clots of CIT patients are more susceptible to t-PA induced lysis compared to healthy individuals.
Heubel-Moenen, Floor C. J. I., Henskens, Yvonne M. C., Verhezen, Paul W. M., Wetzels, Rick J. H., Schouten, Harry C., Beckers, Erik A. M.   +5 more
openaire   +2 more sources

Chemotherapy induced thrombocytopenia treated by four types of platelets concentrates [PDF]

Hospital Pharmacology, 2015
Introduction: Serious adverse event of anticancer chemotherapy is glanulocytopenia and thrombocytopenia which can decrease efficiency of final therapy results. After many years, platelet concentrates transfusion (PCT) is still researching problem without
Nikolić Ljubinka I., Nedeljković Ninoslav D., Jelić Svetislav B., Suvajdžić Vuković Nada D., Fillipović-Lješković Ivana M., Marković Srđan Z., Janković Drina Lj., Kastratović Dragana A.   +7 more
doaj   +1 more source

Acute Immune-Mediated Thrombocytopenia due to Oxaliplatin and Irinotecan Therapy

Case Reports in Oncological Medicine, 2019
We describe a case of a 63-year-old woman with advanced colon cancer and liver metastases who was treated with fluorouracil, leucovorin, and oxaliplatin (FOLFOX) and cetuximab chemotherapy.
Eric L. Tam, Padma L. Draksharam, Jennifer A. Park, Gurinder S. Sidhu   +3 more
doaj   +1 more source

Prevalence and aetiology of moderate and severe thrombocytopenia in a tertiary and quaternary centre in KwaZulu-Natal

African Journal of Laboratory Medicine, 2020
Background: Thrombocytopenia is a common haematological disorder, characterised by platelet counts below 150 × 109/L. The aetiology of thrombocytopenia is multifactorial; notably, in a misdiagnosis this condition may be due to pre-analytical laboratory ...
Ayanda G. Jali, Bongani B. Nkambule
doaj   +1 more source