Results 41 to 50 of about 3,981,458 (213)

Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

Journal of Translational Medicine, 2012
Background Combination of oncolytic vaccinia virus therapy with conventional chemotherapy has shown promise for tumor therapy. However, side effects of chemotherapy including thrombocytopenia, still remain problematic.
Sturm Julia B, Hess Michael, Weibel Stephanie, Chen Nanhai G, Yu Yong A, Zhang Qian, Donat Ulrike, Reiss Cora, Gambaryan Stepan, Krohne Georg, Stritzker Jochen, Szalay Aladar A   +11 more
doaj   +1 more source

Effects of Granules on Chemotherapy-Induced Thrombocytopenia in Gastrointestinal Cancer Patients: A Randomized Controlled Trial

Integrative Cancer Therapies, 2019
Background: To observe clinical effects of Shen Cao granules on thrombocytopenia in patients with gastrointestinal cancer undergoing chemotherapy. Patients and Methods: Patients under a FOLFIRI chemotherapy regimen (n = 92) were randomly divided into ...
Chunfeng Yu MS, Wei Liu MS, Yuejun Mu MS, Aihua Hou MS, Yin Li MS   +4 more
doaj   +1 more source

Bilateral Spontaneous Hemotympanum Secondary to Chemotherapy-Induced Thrombocytopenia

Clinical Medicine Insights: Ear, Nose and Throat, 2013
Objective To present a case of spontaneous, bilateral hemotympanum secondary to chemotherapy-induced thrombocytopenia. Methods Case report and review of the literature. Results Bilateral spontaneous hemotympanum is an exceedingly rare event.
Wong, Peter, Xu, Caroline, Gomaa, Nahla, Ho, Allan   +3 more
openaire   +2 more sources

Optimal management of chemotherapy-induced thrombocytopenia with thrombopoietin receptor agonists. [PDF]

Blood Rev
Chemotherapy-induced thrombocytopenia (CIT) is a common complication of antineoplastic therapy, resulting in antineoplastic therapy dose reductions, treatment delays, treatment discontinuation, and morbid bleeding events. Despite several decades of research into thrombopoietic growth factors in CIT, there are presently no available U.S.
Al-Samkari H.
europepmc   +3 more sources

Aspirin use and bleeding events during thrombocytopenia after autologous stem-cell transplantation for multiple myeloma

Frontiers in Oncology, 2023
BackgroundIn patients with cardiovascular (CV) comorbidities that necessitate antiplatelet therapy (APT), its optimal management during chemotherapy-induced thrombocytopenia remains elusive, as the risk of bleeding has to be balanced against the risk of ...
Nina Rosa Neuendorff, Nina Rosa Neuendorff, Boryana Boshikova, Boryana Boshikova, Lutz Frankenstein, Marietta Kirchner, Christian Rohde, Hartmut Goldschmidt, Norbert Frey, Carsten Müller-Tidow, Karin Jordan, Karin Jordan, Sandra Sauer, Maike Janssen   +13 more
doaj   +1 more source

Thrombopoietin level predicts response to treatment with romiplostim in chemotherapy‐induced thrombocytopenia

American Journal of Hematology, 2021
AbstractChemotherapy‐induced thrombocytopenia (CIT) is a common complication of cancer treatment. Evidence has emerged supporting use of romiplostim to treat CIT but predicting clinical response to romiplostim is not possible. To determine utility of endogenous thrombopoietin (TPO) as a biomarker of romiplostim response, we performed an observational ...
Andrew B. Song, Katayoon Goodarzi, Rebecca Karp Leaf, David J. Kuter, Hanny Al‐Samkari   +4 more
openaire   +2 more sources

ANTICOAGULANT-ASSOCIATED PSEUDOTHROMBOCYTOPENIA: A CASE REPORT

Hematology, Transfusion and Cell Therapy
Introduction: Anticoagulant-dependent pseudothrombocytopenia (PTDA) is characterized by an in vitro reduction in platelet count due to platelet aggregation in blood samples collected with anticoagulants, such as EDTA, where aggregates are erroneously ...
ADES Cucinelli, B Giorno, JBM Oliveira
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Use of romiplostim for antineoplastic therapy-induced thrombocytopenia in gynecologic and breast cancers

Gynecologic Oncology Reports
Objective: Romiplostim is used to treat chemotherapy-induced thrombocytopenia in a variety of tumor types; however, few studies have examined its use in breast and gynecologic cancers.
Sara Moufarrij, Roisin E. O'Cearbhaill, Qin Zhou, Alexia Iasonos, Simon Mantha, Jeffrey Zwicker, Cy R. Wilkins   +6 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source