Results 31 to 40 of about 28,175 (193)

A Case of Recurrent Ovarian Cancer and Therapy-Related Acute Myeloid Leukemia Treated with Azacitidine

Case Reports in Oncology, 2021
Therapy-related myelodysplastic syndrome (tMDS) and acute myeloid leukemia (tAML) are lethal complications of chemotherapy. The incidence rates are expected to increase owing to improvements of cancer treatment.
Kenju Ando, Akihiko Shimomura, Ryo Nasu, Misao Nakanishi, Yukino Kawamura, Akira Hangaishi, Hajime Oishi, Chikako Shimizu   +7 more
doaj   +1 more source

Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia

Case Reports in Oncology, 2018
Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy.
Elizabeth Pan, Eric Hsieh, Caroline Piatek   +2 more
doaj   +1 more source

Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

Journal of Translational Medicine, 2012
Background Combination of oncolytic vaccinia virus therapy with conventional chemotherapy has shown promise for tumor therapy. However, side effects of chemotherapy including thrombocytopenia, still remain problematic.
Sturm Julia B, Hess Michael, Weibel Stephanie, Chen Nanhai G, Yu Yong A, Zhang Qian, Donat Ulrike, Reiss Cora, Gambaryan Stepan, Krohne Georg, Stritzker Jochen, Szalay Aladar A   +11 more
doaj   +1 more source

Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia

BMC Cancer, 2010
Background Preclinical studies demonstrated that small chain RNA fragments accelerate the recovery of platelets numbers in animals exposed to high doses of chemotherapeutic drugs. There is anecdotal data supporting the same application in humans.
Hall John L, Grutsch James F, Daehler MaryAnn, Levin Robert D, Gupta Digant, Lis Christopher G   +5 more
doaj   +1 more source

Bilateral Spontaneous Hemotympanum Secondary to Chemotherapy-Induced Thrombocytopenia

Clinical Medicine Insights: Ear, Nose and Throat, 2013
Objective To present a case of spontaneous, bilateral hemotympanum secondary to chemotherapy-induced thrombocytopenia. Methods Case report and review of the literature. Results Bilateral spontaneous hemotympanum is an exceedingly rare event.
Wong, Peter, Xu, Caroline, Gomaa, Nahla, Ho, Allan   +3 more
openaire   +2 more sources

Research Progress on Mechanism of Tumor-Associated Immune Thrombocytopenia

Zhongliu Fangzhi Yanjiu
Thrombocytopenia is a common complication during the treatment of malignant tumors. It can lead to insufficient doses of chemotherapy drugs or delayed chemotherapy, shorten patients’ survival time, and affect prognosis.
Guimin LIU, Huimin ZHU, Zhiyong CHENG, Wei QIN   +3 more
doaj   +1 more source

Aspirin use and bleeding events during thrombocytopenia after autologous stem-cell transplantation for multiple myeloma

Frontiers in Oncology, 2023
BackgroundIn patients with cardiovascular (CV) comorbidities that necessitate antiplatelet therapy (APT), its optimal management during chemotherapy-induced thrombocytopenia remains elusive, as the risk of bleeding has to be balanced against the risk of ...
Nina Rosa Neuendorff, Nina Rosa Neuendorff, Boryana Boshikova, Boryana Boshikova, Lutz Frankenstein, Marietta Kirchner, Christian Rohde, Hartmut Goldschmidt, Norbert Frey, Carsten Müller-Tidow, Karin Jordan, Karin Jordan, Sandra Sauer, Maike Janssen   +13 more
doaj   +1 more source

Thrombopoietin level predicts response to treatment with romiplostim in chemotherapy‐induced thrombocytopenia

American Journal of Hematology, 2021
AbstractChemotherapy‐induced thrombocytopenia (CIT) is a common complication of cancer treatment. Evidence has emerged supporting use of romiplostim to treat CIT but predicting clinical response to romiplostim is not possible. To determine utility of endogenous thrombopoietin (TPO) as a biomarker of romiplostim response, we performed an observational ...
Andrew B. Song, Katayoon Goodarzi, Rebecca Karp Leaf, David J. Kuter, Hanny Al‐Samkari   +4 more
openaire   +2 more sources

CHEMOTHERAPY-INDUCED THROMBOCYTOPENIA LEADING TO LIFE-THREATENING HYPOVOLEMIC SHOCK IN CERVICAL CANCER: A CASE REPORT

Jurnal Kedokteran Diponegoro
Hypovolemic shock due to acute hemorrhage is a life-threatening condition, particularly in cancer patients undergoing chemotherapy. Although recent studies have established protocols for managing hypovolemic shock in trauma and sepsis, the role of ...
Nurul Fadila, Raveinal Raveinal, Fadrian Fadrian, Roza Mulyana   +3 more
doaj   +1 more source

Use of romiplostim for antineoplastic therapy-induced thrombocytopenia in gynecologic and breast cancers

Gynecologic Oncology Reports
Objective: Romiplostim is used to treat chemotherapy-induced thrombocytopenia in a variety of tumor types; however, few studies have examined its use in breast and gynecologic cancers.
Sara Moufarrij, Roisin E. O'Cearbhaill, Qin Zhou, Alexia Iasonos, Simon Mantha, Jeffrey Zwicker, Cy R. Wilkins   +6 more
doaj   +1 more source