Results 71 to 80 of about 2,538,615 (320)

Chemotherapy versus supportive care in advanced non-small cell lung cancer: improved survival without detriment to quality of life [PDF]

, 2004
BACKGROUND: In 1995 a meta-analysis of randomised trials investigating the value of adding chemotherapy to primary treatment for non-small cell lung cancer (NSCLC) suggested a small survival benefit for cisplatin-based chemotherapy in each of the primary
Brown, J., Fairlamb, D.J., Gower, N.H., Maslove, L., Milroy, R., Napp, V., Parmar, M.K.B., Peake, M.D., Rudd, R.M., Souhami, R.L., Spiro, S.G., Stephens, R.J., Thorpe, H., Waller, D.A., West, P.   +14 more
core   +2 more sources

Antimicrobial resistance of nosocomial Acinetobacter spp. isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Acinetobacter baumannii and related species of the A. baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 568 isolates of Acinetobacter spp ...
Sukhorukova M.V., Edelstein M.V., Skleenova E.Yu., Ivanchik N.V., Shek E.A., Dekhnich A.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

Role of endogenous and exogenous antioxidants in risk of six cancers: evidence from the Mendelian randomization study

Frontiers in Pharmacology, 2023
Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show ...
Jiahao Zhu, Jie Lian, Xin Wang, Ren Wang, Xiangyi Pang, Benjie Xu, Xing Wang, Chenyang Li, Shengjun Ji, Haibo Lu   +9 more
doaj   +1 more source

Mathematical Model of the Impact of Chemotherapy and Anti-Angiogenic Therapy on Drug Resistance in Glioma Growth [PDF]

arXiv, 2023
This research presents a mathematical model of glioma growth dynamics with drug resistance, capturing interactions among five cell populations: glial cells, sensitive glioma cells, resistant glioma cells, endothelial cells, and neuron cells, along with two therapy agent populations: chemotherapy and anti-angiogenic therapy.
arxiv  

A Controlled Comparison of a Twice-Weekly and Three Once-Weekly Regimens in the Initial Treatment of Pulmonary Tuberculosis [PDF]

, 1970
value of a fully supervised twice-weekly regimen of high-dosage isoniazid plus streptomycin in the treatment of newly diagnosed tuberculous patients with drug-sensitive cultures.
Tuberculosis Chemotherapy Centre, Madras
core  

In vitro culture with gemcitabine augments death receptor and NKG2D ligand expression on tumour cells [PDF]

, 2019
Much effort has been made to try to understand the relationship between chemotherapeutic treatment of cancer and the immune system. Whereas much of that focus has been on the direct effect of chemotherapy drugs on immune cells and the release of antigens
A Ashkenazi, A Cerwenka, A Hadji, A Orbach, AP Costa-Pereira, Baryshnikov AYu, C Fionda, H Cho, HA Elrod, I Viard-Leveugle, J Sträter, J Wu, JC Symes, K Yamamoto, L Boldrini, L Galligan, L Siena, M Christgen, M Mottolese, M Müller, M Todaro, M Villa-Morales, MA Park, ME Peter, N Gordon, O Micheau, PB Carvalho-Neto de, RW McGilvray, S Yang, V Almendro, WM Liu, Y Hirooka, Y Kimura   +32 more
core   +2 more sources

Platinum-based chemotherapy plus cetuximab in head and neck cancer.

New England Journal of Medicine, 2008
BACKGROUND Cetuximab is effective in platinum-resistant recurrent or metastatic squamous-cell carcinoma of the head and neck. We investigated the efficacy of cetuximab plus platinum-based chemotherapy as first-line treatment in patients with recurrent or
J. Vermorken, R. Mesía, F. Rivera, É. Remenár, A. Kawecki, S. Rottey, J. Erfán, D. Zabolotnyy, H. Kienzer, D. Cupissol, F. Peyrade, M. Benasso, I. Vynnychenko, D. de Raucourt, C. Bokemeyer, A. Schueler, N. Amellal, R. Hitt   +17 more
semanticscholar   +1 more source

Geriatric Assessment-Driven Intervention (GAIN) on Chemotherapy-Related Toxic Effects in Older Adults With Cancer: A Randomized Clinical Trial.

JAMA Oncology, 2021
Importance Although geriatric assessment-driven intervention improves patient-centered outcomes, its influence on chemotherapy-related toxic effects remains unknown.
Daneng Li, Can‐lan Sun, Heeyoung Kim, E. Soto-Pérez-de-Celis, V. Chung, M. Koczywas, M. Fakih, J. Chao, L. Cabrera Chien, Kemeberly Charles, Simone Fernandes Dos Santos Hughes, V. Katheria, Monica Trent, E. Roberts, R. Jayani, Jeanine Moreno, C. Kelly, M. Sedrak, W. Dale   +18 more
semanticscholar   +1 more source

Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities.
Romanov A.V., Dekhnich A.V., Sukhorukova M.V., Skleenova E.Yu., Ivanchik N.V., Edelstein M.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

A Concurrent Comparison of Intermittent (Twice-Weekly) Isoniazid plus Streptomycin and Daily Isoniazid plus PAS in the Domiciliary Treatment of Pulmonary Tuberculosis [PDF]

, 1964
Previous reports from the Tuberculosis Chemotherapy Centre, Madras, have established that ambulatory treatment of pulmonary tuberculosis with the combination of isoniazid and PAS, administered daily, yields satisfactory results.
Tuberculosis Chemotherapy Centre, Madras
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