Results 11 to 20 of about 19,491 (256)

Antitumor Cannabinoid Chemotypes: Structural Insights [PDF]

Frontiers in Pharmacology, 2019
Cannabis has long been known to limit or prevent nausea and vomiting, lack of appetite, and pain. For this reason, cannabinoids have been successfully used in the treatment of some of the unwanted side effects caused by cancer chemotherapy. Besides their palliative effects, research from the past two decades has demonstrated their promising potential ...
Morales, Paula, Jagerovic, Nadine
openaire   +4 more sources

Transcriptome assemblies for two drug-type cannabis chemotypes by long-read RNA sequencing. [PDF]

Plant Genome
Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Berkowitz O, Jost R, Ng S, Bacic A, Whelan J, Lewsey MG.   +5 more
europepmc   +2 more sources

Novel Toxoplasma gondii inhibitor chemotypes [PDF]

Parasitology International, 2018
We profiled three novel T. gondii inhibitors identified from an antimalarial phenotypic high throughput screen (HTS) campaign: styryl 4-oxo-1,3-benzoxazin-4-one KG3, tetrahydrobenzo[b]pyran KG7, and benzoquinone hydrazone KG8. These compounds inhibit T.
A G, Sanford, T T, Schulze, L P, Potluri, R M, Hemsley, J J, Larson, A K, Judge, S J, Zach, X, Wang, S A, Charman, J L, Vennerstrom, P H, Davis   +10 more
openaire   +2 more sources

Cell‐Based Identification of New IDO1 Modulator Chemotypes [PDF]

Angewandte Chemie, 2021
AbstractThe immunoregulatory enzyme indoleamine‐2,3‐dioxygenase (IDO1) strengthens cancer immune escape, and inhibition of IDO1 by means of new chemotypes and mechanisms of action is considered a promising opportunity for IDO1 inhibitor discovery. IDO1 is a cofactor‐binding, redox‐sensitive protein, which calls for monitoring of IDO1 activity in its ...
Elisabeth Hennes, Philipp Lampe, Lara Dötsch, Nora Bruning, Lisa‐Marie Pulvermacher, Sonja Sievers, Slava Ziegler, Herbert Waldmann   +7 more
openaire   +5 more sources

Foeniculum vulgare Miller, a New Chemotype from Montenegro [PDF]

Plants, 2021
Previous studies relating to prolonged and fractionated distillation procedures highlighted essential oils’ (EOs) chemical composition to be significantly dependent on the extraction duration and harvesting time. As a continuation, a hydrodistillation procedure was applied to ripe fruit material of fennel, Foeniculum vulgare Miller (Apiaceae ...
Mijat Božović, Stefania Garzoli, Svetlana Vujović, Filippo Sapienza, Rino Ragno   +4 more
openaire   +4 more sources

Artemisia gmelinii Web. ex Stechm. within the Buryatian flora: phytocenotic confinedness, composition of essential oil

RUDN Journal of Ecology and Life Safety, 2020
Buryatia as a part of Baikalian Siberia is one of the main centers of origin and morphological diversity of wormwood in Eurasia. There are 48 species and subspecies of wormwood within Buryatian flora, one of which is Artemisia gmelinii Web.
Svetlana V. Zhigzhitzhapova, Svetlana A. Kholboeva, Elena P. Dylenova   +2 more
doaj   +1 more source

Molecular, morphological, and phytochemical evidence for a broad species concept of Plagiochila bifaria (Hepaticae) [PDF]

, 2004
Debate over the synonymy of the European Plagiochila killarniensis and the Neotropical P bifaria of R sect. Arrectae has focused on differences in secondary metabolite composition.
Feldberg, K., Groth, H., Heinrichs, J., Lindner, M., Rycroft, D.S.   +4 more
core   +1 more source

ToxGen: An improved reference database for the identification of type B-trichothecene genotypes in Fusarium [PDF]

, 2017
Type B trichothecenes, which pose a serious hazard to consumer health, occur worldwide in grains. These mycotoxins are produced mainly by three different trichothecene genotypes/chemotypes: 3ADON (3-acetyldeoxynivalenol), 15ADON (15-acetyldeoxynivalenol)
Abarenkov, Kessy, Bilska, Katarzyna, Brankovics, Balázs, Busko, Maciej, Krawczyk, Katarzyna, Kulik, Tomasz, Ostrowska-Kolodziejczak, Anna, Perkowski, Juliusz, Sawicki, Jakub, Stenglein, Sebastian Alberto, van Diepeningen, Anne D.   +10 more
core   +5 more sources

Commercial biocontrol agents reveal contrasting comportments against two mycotoxigenic fungi in cereals: Fusarium Graminearum and Fusarium Verticillioides [PDF]

, 2020
The aim of this study was to investigate the impact of commercialized biological control agents (BCAs) against two major mycotoxigenic fungi in cereals, Fusarium graminearum and Fusarium verticillioides, which are trichothecene and fumonisin producers ...
Durand, Noel, Foutana, Angélique, Martinez, Véronique, Pellan, Lucile, Schorr-Galindo, Sabine, Strub, Caroline   +5 more
core   +1 more source

Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti. [PDF]

, 2019
There is an increased need for improved and affordable insect repellents to reduce transmission of rapidly spreading diseases with high mortality rates.
Dong, Xujun, Ejercito, Jadrian, Guda, Tom, Ray, Anandasankar, Reichert, William, Simon, James E, Wu, Qingli   +6 more
core   +2 more sources