Results 31 to 40 of about 12,690 (274)

Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo. [PDF]

open access: yes, 2017
Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected.
Sowood, D.J.   +11 more
core   +1 more source

Discrimination of Fennel Chemotypes Applying IR and Raman Spectroscopy: Discovery of a New γ-Asarone Chemotype

open access: yesJournal of Agricultural and Food Chemistry, 2014
Various vibrational spectroscopy methods have been applied to classify different fennel chemotypes according to their individual profile of volatile substances. Intact fennel fruits of different chemotypes could be successfully discriminated by attenuated total reflectance Fourier transform infrared (ATR-FTIR) and near infrared (NIR) spectroscopy ...
Krähmer, Andrea   +4 more
openaire   +3 more sources

A survey of Fusarium species and ADON genotype on Canadian wheat grain

open access: yesFrontiers in Fungal Biology, 2022
IntroductionWheat is a staple food that is important to global food security, but in epidemic years, fungal pathogens can threaten production, quality, and safety of wheat grain.
Janice Bamforth   +15 more
doaj   +1 more source

Chemical Characterization of the Essential Oil Compositions of Mentha spicata and M. longifolia ssp. cyprica from the Mediterranean Basin and Multivariate Statistical Analyses

open access: yesMolecules
This present study aims to characterize the essential oil compositions of the aerial parts of M. spicata L. and endemic M. longifolia ssp. cyprica (Heinr. Braun) Harley by using GC-FID and GC/MS analyses simultaneously.
Hasan İsfendiyaroğlu   +5 more
doaj   +1 more source

Chemotype (Cht) properties.

open access: yes, 2015
Chemotype (Cht) properties.
Thomas Rohrlack (319199)   +3 more
core   +1 more source

A new chemotype with promise against Trypanosoma cruzi [PDF]

open access: yesBioorganic & Medicinal Chemistry Letters, 2020
Pyridyl benzamide 2 is a potent inhibitor of Trypanosoma cruzi, but not other protozoan parasites, and had a selectivity-index of ≥10. The initial structure-activity relationship (SAR) indicates that benzamide and sulfonamide functional groups, and N-methylpiperazine and sterically unhindered 3-pyridyl substructures are required for high activity ...
Wang, X.   +8 more
openaire   +4 more sources

Secondary Site Ligand for Integrin αVβ3 Enables Targeted mRNA Delivery

open access: yesAngewandte Chemie, EarlyView.
Non‐orthosteric, low‐affinity ligands for integrin αVβ3, identified by fragment screening, achieve superselective nanoparticle targeting (ακ ≈ 3) of αVβ3‐overexpressing endothelial cells. Unlike traditional arginine–glycine–aspartate decorated particles, these fragment‐functionalized LNPs discriminate cells by receptor density and deliver mRNA to ...
Sebastian Bayer   +7 more
wiley   +2 more sources

A COMPARISON OF DIFFERENT LIPOPOLYSACCHARIDE CHEMOTYPES FROM ESCHERICHIA COLI AND SALMONELLA UPON SYNTHESIS OF TNFα AND IL-6 BY MACROPHAGE-LIKE THP-1 CELLS

open access: yesМедицинская иммунология, 2014
. Present study was performed to investigate the influence of polysaccharide fragment or lipid A upon induction of TNFα and IL-6 cytokines. The study was performed with human THP-1 monocytic leukemia cells that were induced to differentiate into ...
E. V. Voloshina   +4 more
doaj   +1 more source

Comparative Chemical Profiles and Phytotoxic Activity of Essential Oils of Two Ecospecies of Pulicaria undulata (L.) C.A.Mey

open access: yesPlants, 2021
The Asteraceae (Compositae) family is one of the largest angiosperm families that has a large number of aromatic species. Pulicaria undulata is a well-known medicinal plant that is used in the treatment of various diseases due to its essential oil (EO ...
Ahmed M. Abd-ELGawad   +9 more
doaj   +1 more source

Better than Random? The Chemotype Enrichment Problem

open access: yes, 2016
Chemotype enrichment is increasingly recognized as an important measure of virtual screening performance. However, little attention has been paid to producing metrics which can quantify chemotype retrieval.
James L. Melville (2361217)   +1 more
core   +1 more source

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