Results 21 to 30 of about 9,405 (216)
Novel Toxoplasma gondii inhibitor chemotypes [PDF]
Parasitology International, 2018 We profiled three novel T. gondii inhibitors identified from an antimalarial phenotypic high throughput screen (HTS) campaign: styryl 4-oxo-1,3-benzoxazin-4-one KG3, tetrahydrobenzo[b]pyran KG7, and benzoquinone hydrazone KG8. These compounds inhibit T.
A G, Sanford +10 more
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The chemotype core collection of genus Nicotiana
The Plant Journal, 2022 SUMMARYSustainable production of chemicals and improving these biosources by engineering metabolic pathways to create efficient plant‐based biofactories relies on the knowledge of available chemical/biosynthetic diversity present in the plant. Nicotiana species are well known for their amenability towards transformation and other new plant breeding ...
Drapal, Margit +2 more
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Essential Oil Polymorphism of Hungarian Common Thyme ( Willd.) Populations
Natural Product Communications, 2008 The volatile oil compositions of Thymus glabrescens Willd. from eight different localities of Hungary were analyzed by GC/MS. Significant essential oil polymorphism was found: eight new chemovarieties may have been determined, representing a way of ...
Zsuzsanna Pluhár +3 more
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Generalism in Nature…The Great Misnomer: Aphids and Wasp Parasitoids as Examples
Insects, 2019 In the present article we discuss why, in our view, the term ‘generalism’ to define the dietary breadth of a species is a misnomer and should be revised by entomologists/ecologists with the more exact title relating to the animal in question&#
Hugh D. Loxdale +2 more
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Essential Oil Polymorphism of Wild Growing Hungarian Thyme () Populations in the Carpathian Basin
Natural Product Communications, 2010 The volatile oil compositions of Thymus pannonicus All. from nineteen different localities of Hungary were analyzed by GC/MS. The essential oil content of the Hungarian thyme samples varied between very low (0.14 mL/100 g DW) and fairly high (1.9 mL/100 ...
Zsuzsanna Pluhár +3 more
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Detailed Phytochemical Analysis of High- and Low Artemisinin-Producing Chemotypes of Artemisia annua
Frontiers in Plant Science, 2018 Chemical derivatives of artemisinin, a sesquiterpene lactone produced by Artemisia annua, are the active ingredient in the most effective treatment for malaria. Comprehensive phytochemical analysis of two contrasting chemotypes of A.
Tomasz Czechowski +7 more
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Molecules, 2022 Ocimum campechianum Mill. (Peruvian basil) is an essential oil-bearing plant of the Lamiaceae family. Volatile oil produced through steam distillation of Peruvian basil was examined to establish the aromatic and stable isotope profiles of samples (n = 9)
Tyler M. Wilson +5 more
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CHEMOTYPIC Variation in Volatiles and Herbivory for Sagebrush [PDF]
Journal of Chemical Ecology, 2016 Plants that are damaged by herbivores emit complex blends of volatile compounds that often cause neighboring branches to induce resistance. Experimentally clipped sagebrush foliage emits volatiles that neighboring individuals recognize and respond to. These volatiles vary among individuals within a population.
Richard Karban +2 more
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Machine learning approaches to study the structure-activity relationships of LpxC inhibitors
EXCLI Journal : Experimental and Clinical Sciences, 2023 Antimicrobial resistance (AMR) has emerged as one of the global threats to human health in the 21st century. Drug discovery of inhibitors against novel targets rather than conventional bacterial targets has been considered an inevitable strategy for the ...
Tianshi Yu +4 more
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Occurrence of the d-Proline Chemotype in Enzyme Inhibitors [PDF]
Symmetry, 2019 Natural and nonnatural amino acids represent important building blocks for the development of peptidomimetic scaffolds, especially for targeting proteolytic enzymes and for addressing protein–protein interactions. Among all the different amino acids derivatives, proline is particularly relevant in chemical biology and medicinal chemistry due to its ...
Lenci E., Trabocchi A.
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