Results 111 to 120 of about 17,521 (222)

Allelopathic effects of volatile compounds of essential oil from Ravensara aromatica Sonnerat chemotypes

open access: yes, 2013
The chemical compositions of three chemotypes of Ravensara aromatica Sonn. (Lauraceae) leaf essential oils (EOs) was determined by GC and GC/MS. One chemotype rich in aromatic components (methyl chavicol) and two chemotypes rich in terpenic components ...
Andrianjafinandrasana, S.N.   +4 more
core  

Design, Synthesis and Molecular Docking Studies of Some Novel Hydrazone Derivatives Based on Trimetazidine as Selective and Potent AChE Inhibitors

open access: yesDrug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disease, and cholinergic dysfunction is considered one of the fundamental pathological factors of this disease. Guided by the clinically used acetylcholinesterase (AChE) inhibitor donepezil, we explored trimetazidine dihydrochloride as an accessible starting scaffold to generate ...
Muhammed Oğuzhan Doğan   +6 more
wiley   +1 more source

Structures of chemotypes 1a and 2a and their respective deuterated forms examined in this study.

open access: yes, 2018
Structures of chemotypes 1a and 2a and their respective deuterated forms examined in this study.
Alfin D. N. Vaz (172262)   +8 more
core   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood   +7 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Phyto-chemotypes identified in the methanol root extract of R. imbricata by GC/MS.

open access: yes, 2013
Phyto-chemotypes identified in the methanol root extract of R. imbricata by GC/MS.
Rajinder S. Chauhan (178024)   +6 more
core   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu   +2 more
wiley   +1 more source

Phyto-chemotypes identified in the dichloroethane root extract of R. imbricata by GC/MS.

open access: yes, 2013
Phyto-chemotypes identified in the dichloroethane root extract of R. imbricata by GC/MS.
Rajinder S. Chauhan (178024)   +6 more
core   +1 more source

Combating Campylobacter Resistance in Moroccan Poultry Using Essential Oil–Ciprofloxacin Combination

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
With an estimated prevalence of 15.52% in Moroccan poultry, Campylobacter species pose a significant food safety concern. We investigated whether essential oils (EOs) could restore the efficacy of ciprofloxacin against multidrug‐resistant (MDR) strains.
Zineb Soubai   +13 more
wiley   +1 more source

Temperature interacts with jack pine host defences to influence the growth of mountain pine beetle‐associated fungi

open access: yesAgricultural and Forest Entomology, Volume 28, Issue 4, Page 525-534, November 2026.
Optimal growing temperatures varied with mountain pine beetle‐associated fungal species. There was only a marginal impact of temperature on the response of fungi to defensive monoterpenes of novel host pine. Interspecific facilitation occurred for Leptiographuim longiclavatum when grown in Ophiostoma montium‐induced treatments at optimal temperatures ...
Adrienne C. Bailey   +4 more
wiley   +1 more source

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