Results 101 to 110 of about 24,382 (256)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Searching for novel carbonic anhydrase inhibitors: from virtual screening to the lab bench [PDF]

open access: yes, 2013
Carbonic Anhydrases (CAs) are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate both in prokaryotes and eukaryotes.
Cadoni, Roberta   +8 more
core  

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam   +4 more
wiley   +1 more source

Micrografía cuantitativa y perfiles de HPLC y FTIR de Melissa officinalis y Nepeta cataria (Lamiaceae) de Argentina [PDF]

open access: yes, 2014
Melissa officinalis L., so called "Melissa" or "Toronjil", is a perennial aromatic herb, whose leaves are used in traditional medicine as a carminative, digestive and sedative, both in simple as in mixtures. Meanwhile, Nepeta cataria L., commonly called "
Camí, Gerardo Enrique   +6 more
core  

How proteins bind macrocycles [PDF]

open access: yes, 2014
The potential utility of synthetic macrocycles (MCs) as drugs, particularly against low-druggability targets such as protein-protein interactions, has been widely discussed. There is little information, however, to guide the design of MCs for good target
Beglov, Dmitri   +6 more
core   +1 more source

Pharmacognosy and Chemotypes of Passionflower (Passiflora incarnata L.)

open access: yesBiological and Pharmaceutical Bulletin, 2010
Passionflower (Passiflora incarnata L.) is used in phytotherapy as a mild sedative and anxiolytic agent. In the literature it is clear this plant shows considerable qualitative and quantitative variability with respect to its content of C-glycosyl flavones, some of which are used as marker compounds for extracts.
Wohlmuth, Hans   +3 more
openaire   +4 more sources

Divergent roles of ent‐kaurene oxidase paralogs in rice momilactone biosynthesis

open access: yesJournal of Integrative Plant Biology, EarlyView.
Rice contains a five‐gene tandem array of genes encoding members of the ent‐kaurene oxidase (KO) family, with OsKOL4 and OsKOL5 playing divergent roles in momilactone metabolism, but both acting in the production of antifungal and antibacterial phytoalexins, which are important for disease resistance.
Zhibiao Wang   +8 more
wiley   +1 more source

COMPARATIVE STUDY OF THE CHEMICAL COMPOSITION OF AMAPA LATEX FROM Parahancornia amapa AND Brosimum parinarioides BY HPLC-UV-DAD

open access: yesQuímica Nova
A phytochemical study of the latex from P. amapa and B. parinarioides has led to the isolation of nine compounds. From the latex of B. parinarioides, six compounds were isolated: lupeol acetate (1), butyrospermol (2), and its epimer, tirucalla-7,24-dien ...
Rita Cynara de Oliveira Salles   +3 more
doaj   +1 more source

Comparative Analysis of Deoxynivalenol Biosynthesis Related Gene Expression among Different Chemotypes of Fusarium graminearum in Spring Wheat [PDF]

open access: yes, 2016
Fusarium mycotoxins, deoxynivalenol (DON) and nivalenol (NIV) act as virulence factors and are essential for symptom development after initial infection in wheat. To date, 16 genes have been identified in the deoxynivalenol biosynthesis pathway. However,
Chami C. Amarasinghe   +1 more
core   +3 more sources

The BAHD Acyltransferase Gene Family: Evolutionary Dynamics, Biochemical Mechanisms, and Roles in Plant Stress Adaptation

open access: yesPlant Biotechnology Journal, EarlyView.
BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Muhammad Mubashar Zafar   +7 more
wiley   +1 more source

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