Results 121 to 130 of about 11,582 (221)

Transcriptome assemblies for two drug-type cannabis chemotypes by long-read RNA sequencing. [PDF]

Plant Genome
Berkowitz O, Jost R, Ng S, Bacic A, Whelan J, Lewsey MG.   +5 more
europepmc   +1 more source

Sultams as Dual Inhibitors of Human Carbonic Anhydrase and Thioredoxin Reductase

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
A series of sultam‐based N‐acyl derivatives with potential applications as dual TrxR1 and CA inhibitors were synthesized and evaluated. TrxR1 screening identified several active compounds, with inhibitory potency influenced by the type and orientation of substituents.
Aleksandrs Pustenko, Raitis Bobrovs, Venkatesan Saravanan, Kathir Avan, Simone Carradori, Antons Sizovs, Andrea Angeli, Claudiu T. Supuran, Raivis Žalubovskis   +8 more
wiley   +1 more source

Sharply Contrasting Chemotypes Coincide with Aggression and Divergence in Cryptic African Carpenter Ant Populations. [PDF]

J Chem Ecol
Pohl M, Laukamp T, Caspers M, Paczkowski S, Buellesbach J.   +4 more
europepmc   +1 more source

1‐Aryl‐6,7‐Dimethoxy‐3,4‐Dihydroisoquinoline‐2(1H)‐Sulfonamides as hCA XII Selective Inhibitors: Experimental and Theoretical Studies to Interrogate the Isoform Selectivity

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
Experimental and theoretical studies have disclosed the more relevant structural requirements for effective inhibition and an impressing selectivity toward tumor‐expressed hCA XII isoform over hCA II. Human carbonic anhydrase XII (hCA XII) represents an important pharmacological target for different types of cancer.
Federico Ricci, Anna Di Fiore, Andrea Angeli, Laura De Luca, Francesca Mancuso, Davide Esposito, Giuseppina De Simone, Claudiu T. Supuran, Rosaria Gitto   +8 more
wiley   +1 more source

Artemisinin-Related Therapeutic Strategies for Autoimmune Thyroiditis: Chemokine-Receptor Networks, Spatial Thyroid Biology, and Molecular Mechanisms. [PDF]

Drug Des Devel Ther
Sun Y, Yang X, Zhu Q, Yang R.
europepmc   +1 more source

Novel Inhibitors of Carbonic Anhydrase I and II Identified by High Throughput Virtual Screening and Validated by X‐Ray Crystallography

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
High‐throughput virtual screening identifies novel carbonic anhydrase II ligands from large chemical libraries, enabling rapid hit discovery. Structural validation by X‐ray crystallography confirms the predicted binding modes and reveals key protein–ligand interactions.
Asher L. Brandt, Joseph Venditto, Marta Ferraroni, Claudiu T. Supuran, Andrea Angeli   +4 more
wiley   +1 more source

Molecular basis for inhibition of α-thrombin activity by bacterial lipopolysaccharides. [PDF]

Sci Rep
Lira AL, Drew KC, Dantas RLM, Pang J, McCarty OJT.   +4 more
europepmc   +1 more source

<i>Camphora officinarum</i> (Syn. <i>Cinnamomum camphora</i>): Botany, Phytochemistry, Biological Activities, Agro-Industrial Applications, and Biotechnology. [PDF]

Plants (Basel)
Shah K, Dai W, Shen Q, Zhang Y, Guo J, Qiao J, Hu J, Huang L, Yan D, Wang Y, Zuo J, Li Y, Yuan H, Zheng B.   +13 more
europepmc   +1 more source

Development of a Purple-Leaf Perillene Chemotype Line in <i>Perilla frutescens</i> Reveals Incomplete Linkage with Leaf Color. [PDF]

Plants (Basel)
Wei W, Wang B, Li Z, Liu Y, Ji H, Wu Z, Ma G, Sun Y, Zhang T, Liu Y, Feng L, Jin Y, Wang T, Wang Q, Gao Z, Wei J.   +15 more
europepmc   +1 more source

Host Preference Associated With Deoxynivalenol and Nivalenol Chemotypes in Fusarium graminearum, F. asiaticum, and F. meridionale. [PDF]

Mol Plant Pathol
Liu X, Li K, Qiu J, Wang G, Dong F, Zhou Y, Lee YW, Lim JY, Ye W, Shi J, Xu J, Seo JA.   +11 more
europepmc   +1 more source