Results 121 to 130 of about 15,517 (273)
Beyond substrate analogues:new inhibitor chemotypes for glycosyltransferases
Glycosyltransferases (GTs) are a large family of carbohydrate-active enzymes, which act as nature's glycosylation agents. GTs catalyse the transfer of a mono- or oligosaccharide from a glycosyl donor to an individual acceptor, and play a central rote in ...
Tedaldi, Lauren, Wagner, Gerd K.
core +1 more source
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer +24 more
wiley +1 more source
The evolution of major cannabinoids and terpenes during the growth of Cannabis sativa plants was studied. In this work, seven different plants were selected: three each from chemotypes I and III and one from chemotype II.
Schibano, Daniele +9 more
core +1 more source
Graphical abstract illustrating the metabolic dynamics and regulation of terpenoid production in Zanthoxylum armatum callus cultures. On the left, callus initiation and growth from explants are shown, followed by the establishment of suspension cultures.
Sumit Purohit +11 more
wiley +1 more source
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi +8 more
wiley +1 more source
Algal chemotypes identified in methanol extract of S. porticalis by GC/MS.
Algal chemotypes identified in methanol extract of S. porticalis by GC/MS.
Dalip K. Upreti (579134) +9 more
core +1 more source
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato +6 more
wiley +1 more source
Phyto-chemotypes identified in the methanol root extract of R. imbricata by GC/MS.
Phyto-chemotypes identified in the methanol root extract of R. imbricata by GC/MS.
Rajinder S. Chauhan (178024) +6 more
core +1 more source
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley +1 more source

