Results 91 to 100 of about 20,520 (283)

pH-Solubility relations of chenodeoxycholic and ursodeoxycholic acids: physical-chemical basis for dissimilar solution and membrane phenomena.

Journal of Lipid Research, 1980
We examined by titration the electrochemical properties, apparent pK (pK'a), precipitation pH, and undissociated bile acid solubilities of chenodeoxycholic acid and its 7 beta epimer, ursodeoxycholic acid and their glycine conjugates as functions of a ...
H Igimi, M C Carey
doaj  

Understanding the Impact of Ostomy Dejecta Constituents on Peristomal Skin Health and Models for Its Characterisation

International Wound Journal, Volume 22, Issue 6, June 2025.
ABSTRACT An ostomy, or stoma, is a surgically created percutaneous aperture from a hollow organ (e.g., small intestine) to the body's surface. Physicians may recommend an ostomy as a temporary or permanent solution to a range of disorders of the gastrointestinal tract, with up to 130 000 ostomies performed annually in the United States.
Mirella A. Ejiugwo, Julie V. Gawenda, Abram D. Janis, Deborah A. McNamara, Sinéad T. O'Donnell, Shane Browne   +5 more
wiley   +1 more source

Correlations of Amino Acids with Secondary Structure Types: Connection with Amino Acid Structure [PDF]

arXiv, 2005
The correlations of primary and secondary structures were analyzed using proteins with known structure from Protein Data Bank. The correlation values of amino acid type and the eight secondary structure types at distant position were calculated for distances between -25 and 25.
arxiv  

Bile acid formation in man: metabolism of 7α-hydroxy-4-cholesten-3-one in bile fistula patients

Journal of Lipid Research, 1973
7α-Hydroxy-4-cholesten-3-one is thought to be an intermediate in human bile acid synthesis. This conclusion is based on in vivo experiments in animals and on in vitro studies in which homogenates of animal and human livers were used. To further establish
Russell F. Hanson, Peter D. Klein, Gale C. Williams   +2 more
doaj  

Downregulation of host tryptophan-aspartate containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in human macrophage model [PDF]

, 2015
Leishmania are obligate intracellular protozoan parasites of mammalian hosts. Promastigotes of Leishmania are internalized by macrophages and transformed into amastigotes in phagosomes, and replicate in phagolysosomes.
Deepak eKaul, Mohan Lal Dubey, Rakesh eSehgal, Venkata Subba Rao Atluri, Venkateswara Reddy Gogulamudi, Venkateswara Reddy Gogulamudi   +5 more
core   +2 more sources

Serum Metabolite Profile in Progressive Versus Nonprogressive Alcohol‐Related Liver Disease: A Cross‐Sectional Metabolomics Study

Liver International, Volume 45, Issue 6, June 2025.
ABSTRACT Background and Aims Alcohol‐related liver disease (ALD) is a major cause of mortality and disability‐adjusted life years. It is not fully understood why a small proportion of patients develop progressive forms of ALD (e.g., fibrosis and cirrhosis). Differences in the metabolic processes could be behind the individual progression of ALD.
Eemeli Puhakka, Hany Ahmed, Retu Haikonen, Sophie Leclercq, Kati Hanhineva, Luca Maccioni, Camille Amadieu, Marko Lehtonen, Ville Männistö, Jaana Rysä, Peter Stärkel, Olli Kärkkäinen   +11 more
wiley   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 2. Regulation of bile acid synthesis by enterohepatic circulation of bile acids.

Journal of Lipid Research, 1984
Isotope dilution within bile acid pools and radiochemical assessment of cholesterol oxidation to bile acids were methods used to measure short-term feedback regulation of bile acid synthesis in baboons with controlled enterohepatic circulations ...
R N Redinger
doaj  

ACOX2 deficiency: A disorder of bile acid synthesis with transaminase elevation, liver fibrosis, ataxia, and cognitive impairment [PDF]

, 2016
Acyl CoA Oxidase 2 (ACOX2) encodes branched-chain acyl-CoA oxidase, a peroxisomal enzyme believed to be involved in the metabolism of branched-chain fatty acids and bile acid intermediates. Deficiency of this enzyme has not been described previously.
Akyol, G, Bilgüvar, K, Clayton, PT, Dalgiç, B, Esendagli-Yilmaz, G, Günel, M, Jain, D, Lifton, RP, Mazzacuva, F, Sari, S, Vilarinho, S   +10 more
core   +1 more source

The Enteric Neuronal Circuitry: A Key Ignored Player in Nutrient Sensing Along the Gut–Brain Axis

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
The enteric nervous system (ENS) regulates critical physiological functions including gut motility, blood flow, and epithelial secretions. Despite its autonomous ability to execute local functions, its communication with the central nervous system is integral to the maintenance of homeostasis.
Ester Nikolla, Ava Grandberry, Destiné Jamerson, Charles Robb Flynn, Sinju Sundaresan   +4 more
wiley   +1 more source

Linguistic mechanism of the evolution of amino acid frequencies and genomic GC content [PDF]

arXiv, 2006
Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code determines the evolution of amino acid frequencies and genomic GC content.
arxiv