Results 91 to 100 of about 20,810 (232)

Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems

Advanced Sensor Research, Volume 5, Issue 3, March 2026.
Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid, Martina Viola, Maria Vittoria Balli, Guillermo Moreno‐Alcántar, Pierre Picchetti   +4 more
wiley   +1 more source

Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.

Journal of Lipid Research, 1984
Diosgenin and beta-sitosterol (1% in diet) were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism.
K Uchida, H Takase, Y Nomura, K Takeda, N Takeuchi, Y Ishikawa   +5 more
doaj   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Bile acids are associated with baseline and longitudinal amyloid and tau pathology in patients with Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Alzheimer's disease (AD), a neurodegenerative disease, involves early alterations in the gut microbiota. Bile acids (BAs), which are metabolites produced by the microbiota, may impact brain function through the gut‐brain axis. METHODS By reference to multimodal datasets from the Chinese Preclinical Alzheimer's Disease Study (n ...
Wenjie Fu, Xiaowen Chao, Ying Wang, Shu Liu, Jie Wang, Qi Huang, Ying Luan, Peiyang Luo, Yihui Guan, Yingren Mai, Wei Jia, the Alzheimer's Disease Neuroimaging Initiative, Qihao Guo, Tianlu Chen, Xiaowei Ma, Fang Xie   +15 more
wiley   +1 more source

Effect of chenodeoxycholic acid on biliary and urinary bile acids and bile alcohols in cerebrotendinous xanthomatosis; monitoring by high performance liquid chromatography.

Journal of Lipid Research, 1985
Biliary and urinary bile alcohol and bile acid composition has been determined by high performance liquid chromatography in patients with cerebrotendinous xanthomatosis before and after treatment with chenodeoxycholic acid.
A K Batta, S Shefer, M Batta, G Salen
doaj   +1 more source

Ginseng Volatile Oil Alleviates Loperamide‐Induced Constipation in Mice by Regulating the Microbiota/Metabolism/Neural Network

Food Frontiers, Volume 7, Issue 2, March 2026.
GVO relieves constipation mechanisms. GVO decreased the abundance of Firmicutes and increased that of Bacteroidota, thereby ameliorating Lop‐induced gut microbial imbalances. Then the level of 8,9‐DiHETrE was raised, whereas the level of 15(S)‐HpETE was lowered.
Yanan Xu, Mingyue Wang, Meixin Chen, Zhilong Wang, Baoyue Zhang, Xin Wang, Liying Shang, Lequn Zhang, Bowen Sui, Wei Zhang, Jingzhou Zhang, Xueyuan Bai   +11 more
wiley   +1 more source

Inhibition of formyl peptide receptor-1-mediated cell death as a therapy for lethal cutaneous drug reactions in preclinical models

Nature Communications
Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening mucocutaneous adverse drug reactions characterized by disseminated skin and mucosal detachment.
Haruna Kimura, Akito Hasegawa, Tomoki Nishiguchi, Hong Ha Nguyen, Masatoshi Eguchi, Manao Kinoshita, Youichi Ogawa, Takeaki Ozawa, Riichiro Abe   +8 more
doaj   +1 more source

Regulation of bile acid synthesis in the rat: relationship between hepatic cholesterol 7 alpha-hydroxylase activity and portal bile acids.

Journal of Lipid Research, 1995
Bile acid biosynthesis has been believed to be regulated by negative feedback control; however, recent experiments have cast considerable doubts on the concept. The aim of the study was to examine the consensus of the negative feedback regulation of bile
K Fukushima, H Ichimiya, H Higashijima, H Yamashita, S Kuroki, K Chijiiwa, M Tanaka   +6 more
doaj   +1 more source

FXR‐Mediated Atherosclerosis Alleviation by B. animalis F1‐7 Through Bile Acid Metabolism‐Driven Gut–Liver Axis Modulation

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT This study investigates the mechanisms of B. animalis F1‐7 improving atherosclerosis (AS) through bile acid metabolism by using an “antibiotic cocktail” approach in AS model mice. It was found that B. animalis F1‐7 could effectively reduce lipid accumulation in the aorta of mice, alleviate inflammatory responses and improve the intestinal ...
Tianhu Shan, Jiawen Wang, Yanyang Liu, Huaqi Zhang, Zhe Zhang, Lanwei Zhang, Hui Liang, Xi Liang   +7 more
wiley   +1 more source

Quantitative aspects of the interaction of bile acids with human serum albumin.

Journal of Lipid Research, 1982
The interaction of human serum albumin with twelve bile acids (ba) has been studied by equilibrium dialysis technique using 3H- and 14C-labeled bile acids.
A Roda, G Cappelleri, R Aldini, E Roda, L Barbara   +4 more
doaj   +1 more source