Results 81 to 90 of about 2,513,768 (223)

Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.

open access: yesJournal of Lipid Research, 1984
Diosgenin and beta-sitosterol (1% in diet) were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism.
K Uchida   +5 more
doaj   +1 more source

Long‐Term Safety and Efficacy of Obeticholic Acid in Patients With Primary Biliary Cholangitis: Final Results of the POISE Long‐Term Safety Extension

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1083-1096, October 2026.
In the POISE open‐label extension, patients with primary biliary cholangitis with inadequate response or intolerance to ursodeoxycholic acid received long‐term obeticholic acid (OCA) treatment. Findings demonstrated a safety profile consistent with the known characteristics of OCA, with no unexpected safety signals, while supporting sustained efficacy ...
Christopher L. Bowlus   +8 more
wiley   +1 more source

27-Hydroxycholesterol: production rates in normal human subjects

open access: yesJournal of Lipid Research, 1999
We attempted to quantitate production of bile acid via the 27-hydroxylation pathway in six human subjects. After bolus intravenous injection of known amounts of [24-14C]cholic acid and [24-14C]chenodeoxycholic acid, each subject underwent a constant ...
William C. Duane, Norman B. Javitt
doaj   +1 more source

Disturbance‐Associated Plant Communities in Africa's Largest Alpine Ecosystem: Evidence for Long‐Term Anthropogenic Influence

open access: yesApplied Vegetation Science, Volume 29, Issue 4, October/December 2026.
This study provides the first integrated evidence of long‐term human impacts in Ethiopia's Bale Mountains, combining modern vegetation transects with sedimentary steroid and bile acid biomarkers. We identified a sharp 200 m settlement edge and reveal sustained anthropogenic influence from the late Pleistocene, with pastoralism intensifying around 6.5 ...
Mekbib Fekadu   +12 more
wiley   +1 more source

Comparative effects of chenodeoxycholic acid and ursodeoxycholic acid on lipid synthesis in rat liver

open access: yes, 1981
Chenodeoxycholic and ursodeoxycholic acids reduce significantly the hepatic synthesis of lipids in rats. The present study has been carried out using (1-14C)acetate and evaluating its incorporation into different lipidic fractions of the liver by thin ...
Altomonte, Lorenzo   +6 more
core   +1 more source

Enzymatic fluorimetric determination of cholic acid and chenodeoxycholic acid in aqueous solutions and blood serum using a differential kinetic method

open access: yes, 1984
An enzymatic fluorimetric method is described for the determination of chenodeoxycholic acid and its conjugates and of cholic acid and its conjugates in aqueous solutions and serum. The method is based on the oxidation of 7 α-hydroxy bile acids by β-NAD+
Papanastasiou-Diamandi, A.   +2 more
core   +1 more source

Effect of chenodeoxycholic acid on biliary and urinary bile acids and bile alcohols in cerebrotendinous xanthomatosis; monitoring by high performance liquid chromatography.

open access: yesJournal of Lipid Research, 1985
Biliary and urinary bile alcohol and bile acid composition has been determined by high performance liquid chromatography in patients with cerebrotendinous xanthomatosis before and after treatment with chenodeoxycholic acid.
A K Batta, S Shefer, M Batta, G Salen
doaj   +1 more source

Interaction of chenodeoxycholic acid with cholesterol in a model system studied by spin label probe method

open access: yes, 2015
Interaction of cholesterol which is an essential structural component of animal cell membranes that is required to establish proper membrane permeability and fluidity and the bile chenodeoxycholic acid which significantly increased serum total ...
I. Kh. Yusupov2 (735164)   +4 more
core   +1 more source

Regulation of bile acid synthesis in the rat: relationship between hepatic cholesterol 7 alpha-hydroxylase activity and portal bile acids.

open access: yesJournal of Lipid Research, 1995
Bile acid biosynthesis has been believed to be regulated by negative feedback control; however, recent experiments have cast considerable doubts on the concept. The aim of the study was to examine the consensus of the negative feedback regulation of bile
K Fukushima   +6 more
doaj   +1 more source

Clinical evaluation of associated chenodeoxycholic acid and cycloxilic acid treatment

open access: yes, 1978
In this work the clinical impact of associated chenodeoxycholic acid and cycloxilic acid treatment was ...
ALVISI, Vittorio   +2 more
core  

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