Results 81 to 90 of about 2,513,768 (223)
Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.
Diosgenin and beta-sitosterol (1% in diet) were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism.
K Uchida +5 more
doaj +1 more source
In the POISE open‐label extension, patients with primary biliary cholangitis with inadequate response or intolerance to ursodeoxycholic acid received long‐term obeticholic acid (OCA) treatment. Findings demonstrated a safety profile consistent with the known characteristics of OCA, with no unexpected safety signals, while supporting sustained efficacy ...
Christopher L. Bowlus +8 more
wiley +1 more source
27-Hydroxycholesterol: production rates in normal human subjects
We attempted to quantitate production of bile acid via the 27-hydroxylation pathway in six human subjects. After bolus intravenous injection of known amounts of [24-14C]cholic acid and [24-14C]chenodeoxycholic acid, each subject underwent a constant ...
William C. Duane, Norman B. Javitt
doaj +1 more source
This study provides the first integrated evidence of long‐term human impacts in Ethiopia's Bale Mountains, combining modern vegetation transects with sedimentary steroid and bile acid biomarkers. We identified a sharp 200 m settlement edge and reveal sustained anthropogenic influence from the late Pleistocene, with pastoralism intensifying around 6.5 ...
Mekbib Fekadu +12 more
wiley +1 more source
Chenodeoxycholic and ursodeoxycholic acids reduce significantly the hepatic synthesis of lipids in rats. The present study has been carried out using (1-14C)acetate and evaluating its incorporation into different lipidic fractions of the liver by thin ...
Altomonte, Lorenzo +6 more
core +1 more source
An enzymatic fluorimetric method is described for the determination of chenodeoxycholic acid and its conjugates and of cholic acid and its conjugates in aqueous solutions and serum. The method is based on the oxidation of 7 α-hydroxy bile acids by β-NAD+
Papanastasiou-Diamandi, A. +2 more
core +1 more source
Biliary and urinary bile alcohol and bile acid composition has been determined by high performance liquid chromatography in patients with cerebrotendinous xanthomatosis before and after treatment with chenodeoxycholic acid.
A K Batta, S Shefer, M Batta, G Salen
doaj +1 more source
Interaction of cholesterol which is an essential structural component of animal cell membranes that is required to establish proper membrane permeability and fluidity and the bile chenodeoxycholic acid which significantly increased serum total ...
I. Kh. Yusupov2 (735164) +4 more
core +1 more source
Bile acid biosynthesis has been believed to be regulated by negative feedback control; however, recent experiments have cast considerable doubts on the concept. The aim of the study was to examine the consensus of the negative feedback regulation of bile
K Fukushima +6 more
doaj +1 more source
Clinical evaluation of associated chenodeoxycholic acid and cycloxilic acid treatment
In this work the clinical impact of associated chenodeoxycholic acid and cycloxilic acid treatment was ...
ALVISI, Vittorio +2 more
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