Results 71 to 80 of about 2,513,768 (223)

Metabolism of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid by rat liver in vivo and in vitro.

Journal of Lipid Research, 1979
The metabolism of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid was studied in the bile fistula rats and in preparations from rat liver homogenates.
J Gustafsson
doaj   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li, Yong Zhang, Kaishuang Cai, Shaojun Deng, Chaofeng Tan, Yunjie Li, Wenjin Liang   +6 more
wiley   +1 more source

Identification of (24E)-3 alpha,7 alpha-dihydroxy-5 beta-cholest-24-enoic acid and (24R,25S)-3 alpha,7 alpha,24-trihydroxy-5 beta-cholestanoic acid as intermediates in the conversion of 3 alpha,7 alpha-dihydroxy-5 beta-cholestanoic acid to chenodeoxycholic acid in rat liver homogenates.

Journal of Lipid Research, 1994
Studies of chemical structure of the intermediates in the biosynthetic sequence between 3 alpha,7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) and chenodeoxycholic acid have been undertaken. Radiolabeled DHCA was incubated with a rat liver preparation.
M. Une, A. Inoue, T. Kurosawa, M. Tohma, T. Hoshita   +4 more
doaj   +1 more source

Modulating the Gut–Ovarian Axis: Mechanistic Rationale and the Limits of Current Evidence for Probiotics in Female Reproductive Aging

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Selected orally administered probiotics and functional‐food interventions may alter gut microbial ecology and intestinal barrier function. Microbiota‐derived metabolites, microbial components, and endocrine signals—including short‐chain fatty acids, bile acids, tryptophan metabolites, and lipopolysaccharide—may influence systemic immune, metabolic, and
Meiqi Chen, Qi Su, Mengshuang Sun, He Zhang, Jin Xu, Chenxi Zhang, Yanbo Wang   +6 more
wiley   +1 more source

Comparative Formation of Lithocholic Acid From Chenodeoxycholic and Ursodeoxycholic Acids in the Colon

, 1982
The comparative rate of formation of lithocholic acid from chenodeoxycholic acid and its 7β epimer, ursodeoxycholic acid, was studied in human subjects and in a rhesus monkey.
Sarva, Rajendra P., Sembrat, Roger F., Ceryak, Susan, Bazzoli, Franco, Fromm, Hans   +4 more
core   +1 more source

The ionization behavior of bile acids in different aqueous environments.

Journal of Lipid Research, 1987
The ionization behavior of cholic acid, deoxycholic acid, and chenodeoxycholic acid in a variety of physiologically important molecular environments was studied using 13C NMR spectroscopy.
D J Cabral, J A Hamilton, D M Small
doaj   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Biliary bile acids of fruit pigeons and doves (Columbiformes): presence of 1-beta-hydroxychenodeoxycholic acid and conjugation with glycine as well as taurine.

Journal of Lipid Research, 1994
The biliary bile acid composition of 30 species of pigeons and doves belonging to seven genera in the avian order Columbiformes was determined using TLC, HPLC, GLC/MS, LSIMS, and NMR.
L.R Hagey, C.D Schteingart, H T Ton-Nu, A.F Hofmann   +3 more
doaj   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Effect of short-term administration of chenodeoxycholic acid on serum HDV RNA.

, 2015
Three individuals with chronic HBV/HDV coinfection (circle, triangle and square) were administered chenodeoxycholic acid 15 mg/kg daily orally in three doses. (A) Serum HDV RNA, (B) serum HBV DNA and (C) HBsAg were determined before the first dose and at
Michael P. Manns (92947), Beate Sodeik (191751), Kathrin Sprinzl (689014), Cláudia Pinto Marques Souza de Oliveira (689016), Verena Schlaphoff (220564), Lisa Sandmann (689013), Christoph Sarrazin (48298), Isabel Veloso Alves Pereira (689011), Florian Vondran (689015), Bettina Buchmann (689012), Katinka Döhner (191742), Sandra Ciesek (345033), Thomas von Hahn (345025)   +12 more
core   +1 more source