Results 51 to 60 of about 758 (131)

Cerebrotendinous xanthomatosis: defective liver mitochondrial hydroxylation of chenodeoxycholic acid precursors.

Journal of Lipid Research, 1981
Oxidation of the side chain of 5 beta-cholestane-3 alpha, 7 alpha-diol, 7 alpha-hydroxy-4-cholesten-3-one, and 5-cholestene-3 beta, 7 alpha-diol has been studied in subcellular fractions of liver from a patient with cerebrotendinous xanthomatosis (CTX ...
H Oftebro, I Björkhem, F C Størmer, J I Pedersen   +3 more
doaj   +1 more source

Interaction of the Gut Microbiota and the Enteric Nervous System: Implications in Gastrointestinal Disorders Associated With Autism Spectrum Disorder

Autism Research, Volume 19, Issue 8, August 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, restricted interests, and repetitive behaviors. In addition to these core behavioral symptoms, gastrointestinal (GI) disorders are frequently reported, ranging from severe constipation to diarrhea.
Baptiste Ganachaud, María José Mendoza‐León, Justine Marchix, Alonso Fernandez Tello, Catherine Le Berre Scoul, Ma Cecilia Opazo, Michel Neunlist, Claudia A. Riedel, Martial Caillaud, Hélène Boudin   +9 more
wiley   +1 more source

Metabolism of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid by rat liver in vivo and in vitro.

Journal of Lipid Research, 1979
The metabolism of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid was studied in the bile fistula rats and in preparations from rat liver homogenates.
J Gustafsson
doaj   +1 more source

The Postprandial Chronobiome in Interorgan Glucose Homeostasis

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
The postprandial chronobiome framework proposes that meal‐timed oscillations in microbial communities and metabolites may interact with host tissue clocks to shape glucose handling. The liver is the best‐supported temporal interpreter, while phase‐aware human studies are needed to establish causal interorgan effects.
Josko Bozic, Roko Santic, Marko Kumric
wiley   +1 more source

Identification of (24E)-3 alpha,7 alpha-dihydroxy-5 beta-cholest-24-enoic acid and (24R,25S)-3 alpha,7 alpha,24-trihydroxy-5 beta-cholestanoic acid as intermediates in the conversion of 3 alpha,7 alpha-dihydroxy-5 beta-cholestanoic acid to chenodeoxycholic acid in rat liver homogenates.

Journal of Lipid Research, 1994
Studies of chemical structure of the intermediates in the biosynthetic sequence between 3 alpha,7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) and chenodeoxycholic acid have been undertaken. Radiolabeled DHCA was incubated with a rat liver preparation.
M. Une, A. Inoue, T. Kurosawa, M. Tohma, T. Hoshita   +4 more
doaj   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

The ionization behavior of bile acids in different aqueous environments.

Journal of Lipid Research, 1987
The ionization behavior of cholic acid, deoxycholic acid, and chenodeoxycholic acid in a variety of physiologically important molecular environments was studied using 13C NMR spectroscopy.
D J Cabral, J A Hamilton, D M Small
doaj   +1 more source

The Role of Gut Microbiota in Liver Regeneration After Partial Hepatectomy: New Evidence From Animal and Human Studies

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Partial hepatectomy (PH) reshapes gut microbiota composition, resulting in the release of microbial metabolites and components, including short chain fatty acids (SCFAs)/β‐hydroxybutyric acid (BHB), bacterial DNA and extracellular vesicles (EVs), bile acids (deoxycholic acid, DCA), and aminobenzoate degradation products.
Roberto Loi, Gabriella Simbula, Andrea Caddeo, Monica Pibiri   +3 more
wiley   +1 more source

Biliary bile acids of fruit pigeons and doves (Columbiformes): presence of 1-beta-hydroxychenodeoxycholic acid and conjugation with glycine as well as taurine.

Journal of Lipid Research, 1994
The biliary bile acid composition of 30 species of pigeons and doves belonging to seven genera in the avian order Columbiformes was determined using TLC, HPLC, GLC/MS, LSIMS, and NMR.
L.R Hagey, C.D Schteingart, H T Ton-Nu, A.F Hofmann   +3 more
doaj   +1 more source

Insights Into Gut Microbiota and Metabolic Alterations in Type 1 Diabetes Mellitus

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
Caroline Fogagnolo, Gabriela Ueta Ortiz, Adelino Sanchez Ramos da Silva, Ellen Cristini de Freitas   +3 more
wiley   +1 more source