Results 61 to 70 of about 758 (131)

27-Hydroxycholesterol: production rates in normal human subjects

Journal of Lipid Research, 1999
We attempted to quantitate production of bile acid via the 27-hydroxylation pathway in six human subjects. After bolus intravenous injection of known amounts of [24-14C]cholic acid and [24-14C]chenodeoxycholic acid, each subject underwent a constant ...
William C. Duane, Norman B. Javitt
doaj   +1 more source

Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.

Journal of Lipid Research, 1984
Diosgenin and beta-sitosterol (1% in diet) were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism.
K Uchida, H Takase, Y Nomura, K Takeda, N Takeuchi, Y Ishikawa   +5 more
doaj   +1 more source

Regulation of bile acid synthesis in the rat: relationship between hepatic cholesterol 7 alpha-hydroxylase activity and portal bile acids.

Journal of Lipid Research, 1995
Bile acid biosynthesis has been believed to be regulated by negative feedback control; however, recent experiments have cast considerable doubts on the concept. The aim of the study was to examine the consensus of the negative feedback regulation of bile
K Fukushima, H Ichimiya, H Higashijima, H Yamashita, S Kuroki, K Chijiiwa, M Tanaka   +6 more
doaj   +1 more source

Inhibition of formyl peptide receptor-1-mediated cell death as a therapy for lethal cutaneous drug reactions in preclinical models

Nature Communications
Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening mucocutaneous adverse drug reactions characterized by disseminated skin and mucosal detachment.
Haruna Kimura, Akito Hasegawa, Tomoki Nishiguchi, Hong Ha Nguyen, Masatoshi Eguchi, Manao Kinoshita, Youichi Ogawa, Takeaki Ozawa, Riichiro Abe   +8 more
doaj   +1 more source

Effect of chenodeoxycholic acid on biliary and urinary bile acids and bile alcohols in cerebrotendinous xanthomatosis; monitoring by high performance liquid chromatography.

Journal of Lipid Research, 1985
Biliary and urinary bile alcohol and bile acid composition has been determined by high performance liquid chromatography in patients with cerebrotendinous xanthomatosis before and after treatment with chenodeoxycholic acid.
A K Batta, S Shefer, M Batta, G Salen
doaj   +1 more source

Quantitative aspects of the interaction of bile acids with human serum albumin.

Journal of Lipid Research, 1982
The interaction of human serum albumin with twelve bile acids (ba) has been studied by equilibrium dialysis technique using 3H- and 14C-labeled bile acids.
A Roda, G Cappelleri, R Aldini, E Roda, L Barbara   +4 more
doaj   +1 more source

Biotransformation of chenodeoxycholic acid by Pseudomonas species NCIB 10590 under anaerobic conditions.

Journal of Lipid Research, 1983
The metabolism of chenodeoxycholic acid by Pseudomonas sp. NCIB 10590 under strict anaerobic conditions was studied. A range of unsaturated acidic and neutral metabolites were isolated and identified.
R W Owen, M J Hill, R F Bilton
doaj   +1 more source

Measurement of sulfated and nonsulfated bile acids in human serum and urine

Journal of Lipid Research, 1974
Amberlite XAD-2 was used to extract bile acids from urine or diluted serum of patients with hepatobiliary diseases. Columns containing Sephadex LH-20 were then used to separate the sulfated and nonsulfated bile acids.
Isao Makino, Kenjiro Shinozaki, Shoichi Nakagawa, Keimei Mashimo   +3 more
doaj   +1 more source

Lymphatic transport of bile acids in man

Journal of Lipid Research, 1982
The possibility of a lymphatic transport of bile acids in man was investigated. Four patients were studied 2-4 weeks after renal transplantation.
S Ewerth, I Björkhem, K Einarsson, L Ost   +3 more
doaj   +1 more source

High-concentrate diet decreases lamb fatty acid contents by regulating bile acid composition

Food Chemistry: X
Feeding sheep with high-concentrate diet (HCD) to shorten production cycle is a well-developed feeding strategy to increase lamb production. Here, metabolomics were performed to explore the mechanism that HCD changes lamb nutrition composition ...
Kaizhi Zheng, Liangyong Guo, Yang Cao, Yuyang Yin, Hui Gao, Xiaowei Zhang, Junfang Jiang, Jinbing Li, Xin Huang, Kui Li, Sangang He   +10 more
doaj   +1 more source