Results 61 to 70 of about 2,513,768 (223)
Journal of Lipid Research, 1990 This report describes the chemical synthesis of two new bile salt analogues, namely sodium 3 alpha,7 alpha-dihydroxy-5 beta-cholane-24-sulfonate and sodium 3 alpha,7 beta-dihydroxy-5 beta-cholane-24-sulfonate from chenodeoxycholic acid and ...
K Kihira +5 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1358-1367, November 2026.Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving supratherapeutic OCA doses (100–250 mg).
Abigail K. Mayo +4 more
wiley +1 more source
Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]
, 1991 While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Ritter, Christoph von +3 more
core +1 more source
Journal of Lipid Research, 1982 Whole cells and cell extracts of Eubacterium species V. P. I. 12708 7-dehydroxylated [3H]ursodeoxycholic acid or [14C]chenodeoxycholic forming lithocholic acid.
B A White, R J Fricke, P B Hylemon
doaj +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.ABSTRACT The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short‐chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distinguishes established findings from hypotheses.
Ruijun Wang +4 more
wiley +1 more source
A new non-enzymatic route to chenodeoxycholic acid
, 1996 A novel route for the production of the chenodeoxycholic acid is described, based on the selective non-enzymatic reduction of dehydrocholic acid. The relative reactivity scale was established to be in the order: 12-keto (1), 7-keto (2), 3-keto (17.5)
MEDICI, Alessandro +3 more
core +1 more source
Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACT Background Gastric cancer (GC) has posed a severe threat to human health. Metabolomics analysis has been applied in the context of multiple diseases, offering new perspectives for the development of non‐invasive detections. Objective We aimed to develop a diagnostic model for GC based on a serum bile acid (BA) panel.
Nuo Yao +10 more
wiley +1 more source
Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects [PDF]
, 2008 A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) – a condition with unknown aetiology.
Bajor, Antal
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Journal of Lipid Research, 1981 Oxidation of the side chain of 5 beta-cholestane-3 alpha, 7 alpha-diol, 7 alpha-hydroxy-4-cholesten-3-one, and 5-cholestene-3 beta, 7 alpha-diol has been studied in subcellular fractions of liver from a patient with cerebrotendinous xanthomatosis (CTX ...
H Oftebro +3 more
doaj +1 more source
Cancer Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav +4 more
wiley +1 more source