Results 11 to 20 of about 5,134,427 (306)

Bile acid metabolomics identifies chenodeoxycholic acid as a therapeutic agent for pancreatic necrosis. [PDF]

Cell Rep Med, 2023
Zhu Q, Yuan C, Dong X, Wang Y, Li B, Tu B, Chen W, Xu X, Gong W, Xiao W, Ding Y, Hu L, Li W, Lu G.   +13 more
europepmc   +2 more sources

Chenodeoxycholic acid suppresses AML progression through promoting lipid peroxidation via ROS/p38 MAPK/DGAT1 pathway and inhibiting M2 macrophage polarization. [PDF]

Redox Biol, 2022
Liu J, Wei Y, Jia W, Can C, Wang R, Yang X, Gu C, Liu F, Ji C, Ma D.   +9 more
europepmc   +2 more sources

Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms [PDF]

Journal of Pharmacology and Experimental Therapeutics, 2018
Cen Guo, Carl LaCerte, Jeffrey E. Edwards, Kenneth R. Brouwer, Kim L. R. Brouwer   +4 more
openalex   +2 more sources

Cerebrotendinous xanthomatosis-associated diarrhea and response to chenodeoxycholic acid treatment. [PDF]

JIMD Rep, 2020
In patients with cerebrotendinous xanthomatosis (CTX), chronic diarrhea is one of the earliest and main symptoms of the disease. In the current study, we evaluated the characteristics of the diarrhea and its response to chenodeoxycholic acid (CDCA ...
Brass EP, Stelten BML, Verrips A.
europepmc   +2 more sources

Efficacy of Magnesium Trihydrate of Ursodeoxycholic Acid and Chenodeoxycholic Acid for Gallstone Dissolution: A Prospective Multicenter Trial

Gut and Liver, 2015
Background/AimsCholecystectomy is necessary for the treatment of symptomatic or complicated gallbladder (GB) stones, but oral litholysis with bile acids is an attractive alternative therapeutic option for asymptomatic or mildly symptomatic patients. This
J. Hyun, H. Lee, Chang Duck Kim, S. Dong, Seung-Ok Lee, J. Ryu, Don Haeng Lee, Seok Jeong, Tae Nyeun Kim, Jin Lee, D. Koh, E. Park, I. Lee, B. Yoo, J. Kim   +14 more
doaj   +2 more sources

Study on the Factors Influencing the Extraction of Chenodeoxycholic Acid from Duck Bile Paste by Calcium Salt Method [PDF]

, 2018
New extraction technology of chenodeoxycholic acid from duck bile paste by calcium salt was investigated. The optimum conditions of extraction were determined by orthogonal experimental design.
Xiangzheng Hu, Na Feng, Jiaqi Zhang
openalex   +2 more sources

The safety and effectiveness of chenodeoxycholic acid treatment in patients with cerebrotendinous xanthomatosis: two retrospective cohort studies. [PDF]

Neurol Sci, 2020
Objective To evaluate the safety and effectiveness of chenodeoxycholic acid (CDCA) treatment in patients with cerebrotendinous xanthomatosis (CTX). Methods Two retrospective cohort studies were conducted in CTX patients who underwent CDCA treatment: one ...
Verrips A, Dotti MT, Mignarri A, Stelten BML, Verma S, Federico A.   +5 more
europepmc   +2 more sources

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients [PDF]

Journal of Clinical Endocrinology and Metabolism, 2015
Haoyong Yu, Yan Ni, Yuqian Bao, Pin Zhang, Aihua Zhao, Tianlu Chen, Guoxiang Xie, Yinfang Tu, Lei Zhang, Mingming Su, Li Wei, Wei Jia, Weiping Jia   +12 more
openalex   +2 more sources

Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C‐III [PDF]

Journal of Internal Medicine, 2017
The natural farnesoid X receptor (FXR) agonist chenodeoxycholic acid (CDCA) suppresses hepatic cholesterol and bile acid synthesis and reduces biliary cholesterol secretion and triglyceride production.
Moumita Ghosh Laskar, Mats Eriksson, Mats Rudling, Bo Angelin   +3 more
openalex   +2 more sources