Results 21 to 30 of about 5,134,427 (306)

Metabolism of potential precursors of chenodeoxycholic acid in cerebrotendinous xanthomatosis (CTX).

Journal of Lipid Research, 1979
In patients with cerebrotendinous xanthomatosis (CTX), diminished cholic acid production is associated with incomplete oxidation of the cholesterol side chain and the excretion of C(25)-hydroxy bile alcohols.
G Salen, S Shefer, E H Mosbach, S Hauser, B I Cohen, G Nicolau   +5 more
doaj   +1 more source

Experimental isovalthinuria. III. Induction by bile acids, and hypocholesterolemic agents [PDF]

, 1963
Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in ...
Ubuka, Toshihiko
core   +1 more source

Purification of Hyodeoxycholic Acid and Chenodeoxycholic Acid from Pig Bile Saponification Solution Using Column Chromatography [PDF]

Chemical and Biochemical Engineering Quarterly
The purpose of this study was to purify hyodeoxycholic acid and chenodeoxycholic acid from pig bile saponification solution using column chromatography. The optimal resin was selected through static adsorption experiments.
B. Liu, T. Chen, X. Chen, X. Li, K. Abudureheman, S. Hu, X. Gong   +6 more
doaj   +1 more source

Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]

, 2003
Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J., Göke, B., Hay, U., Marsteller, I., Ochsenkühn, Thomas, Paumgartner, Gustav, Sackmann, M.   +6 more
core   +1 more source

Suitability of [11,12-3H2]chenodeoxycholic acid and [11,12-3H2]lithocholic acid for isotope dilution studies of bile acid metabolism in man

Journal of Lipid Research, 1977
Studies were carried out to assess the stability of the label in [11,12-3H2]chenodeoxycholic acid and [11,12-3H2]lithocholic acid during enterohepatic cycling and thus define the suitability of these tracers for isotope dilution studies of bile acids in ...
P Y Ng, R N Allan, A F Hofmann
doaj   +1 more source

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell, Ahlberg, Balasubramaniam, Barlett, Bernd Seifferth, Berr, Berr, Berr, Berr, Carey, Carey, Carulli, Cohen, Cohen, Coleman, Dam, Delchier, Dieter Jüngst, Everson, Frieder Berr, Glenn, Goodnight, Gustav Paumgartner, Harris, Hofmann, Holan, Holzbach, Joseph Holl, Juniper, Kaludzny, Kelly, Kuroki, Leaf, Lee, Lippel, Lorenz, Magnuson, Marks, Nestel, Nestel, O'Leary, Parhofer, Paul, Phillipson, Pomeranz, Ramond, Robins, Robins, Sanders, Scobey, Sedaghat, Snedecor, Strasberg, Sven Fischer, Sömjen, Ventura, von Schacky, Wagner, Wechsler, Werner O. Richter   +59 more
core   +1 more source

Chenodeoxycholic Acid Ameliorates AlCl3-Induced Alzheimer’s Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats

Molecules, 2019
Insulin resistance is a major risk factor for Alzheimer’s disease (AD). Chenodeoxycholic acid (CDCA) and synthetic Farnesoid X receptor (FXR) ligands have shown promising outcomes in ameliorating insulin resistance associated with various medical ...
F. Bazzari, D. Abdallah, H. El-Abhar
semanticscholar   +1 more source

7alpha-Dehydroxylation of cholic acid and chenodeoxycholic acid by Clostridium leptum.

Journal of Lipid Research, 1979
The rate of 7alpha-dehydroxylation of primary bile acids was quantitatively measured radiochromatographically in anaerobically washed whole cell suspensions of Clostridium leptum.
E J Stellwag, P B Hylemon
doaj   +1 more source

Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells [PDF]

, 2009
In patients with bile acid malabsorption, high concentrations of bile acids enter the colon and stimulate Cl− and fluid secretion, thereby causing diarrhoea. However, deoxycholic acid (DCA), the predominant colonic bile acid, is normally present at lower
Alan F. Hofmann, Barcelo, Barrett, Bertelsen, Cartwright, Chadwick, Cheng, Cheng, Christine Marsh, Dawson, Dawson, Devor, Dharmsathaphorn, Fernandez-Banares, Gail Ferguson, Gelbmann, Gordon, Hamilton, Hofmann, J-P, Kalia, Keely, Keely, Keely, Khurana, Kok, Kruis, Magdalena S. Mroz, Mauricio, Mekjian, Merchant, Michael M. Scharl, Milovic, Montrose, Muhlbauer, Münch, Niamh Keating, Nyhlin, Potter, Raimondi, Smith, Stephen J. Keely, Teem, Ung, Venkatasubramanian, Weihrauch   +45 more
core   +1 more source

An in vivo evaluation of the quantitative significance of several potential pathways to cholic and chenodeoxycholic acids from cholesterol in man

Journal of Lipid Research, 1980
The present study was designed to obtain more definitive information in man on the metabolic pathways to chenodeoxycholic acid and to cholic acid via a pathway not involving an initial 7 alpha-hydroxylation of cholesterol. Four bile fistula patients were
L Swell, J Gustafsson, C C Schwartz, L G Halloran, H Danielsson, Z R Vlahcevic   +5 more
doaj   +1 more source