Results 41 to 50 of about 346,815 (169)

Colchicine Is a Weapon for Managing the Heart Disease Among Interstitial Lung Disease With Viral Infection: Have We Found the Holy Grail?

Frontiers in Cardiovascular Medicine, 2022
BackgroundThis study investigated the effect of colchicine use on the risks of heart disease (HD), pericarditis, endocarditis, myocarditis, cardiomyopathy, cardiac arrhythmia, and cardiac failure in patients having interstitial lung disease (ILD) with ...
Jun-Jun Yeh, Jun-Jun Yeh, Tuey-Wen Hung, Cheng-Li Lin, Cheng-Li Lin, Tsung-Tse Chen, Pei-Xuan Liw, Ya-Lun Yu, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao   +11 more
doaj   +1 more source

A specific example of our predictions for CTCF ChIA-PET interactions on chromosome 10 in GM12878 at 10-kb resolution.

, 2023
From top to bottom: KR-normalized Hi-C, CTCF, ground-truth ChIA-PET, and our predicted ChIA-PET. (TIFF)
Zheng Wang (25883), Tong Liu (107783)
core   +1 more source

A specific example of our predictions for CTCF ChIA-PET on chromosome 6 in HeLa at 10-kb resolution.

, 2023
From top to bottom: KR-normalized Hi-C, CTCF coverage at 10-kb resolution, ground-truth ChIA-PET, and our predicted ChIA-PET.
Zheng Wang (25883), Tong Liu (107783)
core   +1 more source

When ChIA PETs meet Hi-C [PDF]

Nature Methods, 2009
Two methods enable the drawing of genome-wide chromatin interaction maps: one looks at protein-independent folding principles, the other at protein-mediated functional interactions.
openaire   +1 more source

Chromatin loops associated with active genes and heterochromatin shape rice genome architecture for transcriptional regulation

Nature Communications, 2019
Three-dimensional genome organization and its effect on transcription remain elusive in rice. Here, the authors map promoter–promoter interactions and heterochromatin interactions using ChIA-PET and reveal spatial correlation between the genetic ...
Lun Zhao, Shuangqi Wang, Zhilin Cao, Weizhi Ouyang, Qing Zhang, Liang Xie, Ruiqin Zheng, Minrong Guo, Meng Ma, Zhe Hu, Wing-Kin Sung, Qifa Zhang, Guoliang Li, Xingwang Li   +13 more
doaj   +1 more source

Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation

Genome Biology, 2020
We present Mustache, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps.
Abbas Roayaei Ardakany, Halil Tuvan Gezer, Stefano Lonardi, Ferhat Ay   +3 more
doaj   +1 more source

Predicting enhancer-promoter interaction based on epigenomic signals

Frontiers in Genetics, 2023
Introduction: The physical interactions between enhancers and promoters are often involved in gene transcriptional regulation. High tissue-specific enhancer-promoter interactions (EPIs) are responsible for the differential expression of genes ...
Leqiong Zheng, Leqiong Zheng, Leqiong Zheng, Li Liu, Wen Zhu, Wen Zhu, Yijie Ding, Fangxiang Wu   +7 more
doaj   +1 more source

Chromatin interaction maps reveal genetic regulation for quantitative traits in maize

Nature Communications, 2019
Spatial organization of regulatory elements and its impact on gene expression in plants remain unclear. Here, the authors construct maize chromatin interaction maps using chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) and show ...
Yong Peng, Dan Xiong, Lun Zhao, Weizhi Ouyang, Shuangqi Wang, Jun Sun, Qing Zhang, Pengpeng Guan, Liang Xie, Wenqiang Li, Guoliang Li, Jianbing Yan, Xingwang Li   +12 more
doaj   +1 more source

To Investigate the Risk of Herpes Zoster in Women With Endometriosis: A Taiwan National Population-Based Cohort Study

Frontiers in Medicine, 2021
Background: The objective of this study is to investigate the occurrence of herpes zoster (HZ) in patients with endometriosis.Methods: This retrospective population-based cohort study was conducted using the Taiwan National Health Insurance Research ...
Chao-Yu Hsu, Chao-Yu Hsu, Chao-Yu Hsu, Chao-Yu Hsu, Chao-Yu Hsu, Der-Shin Ke, Cheng-Li Lin, Cheng-Li Lin, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao   +11 more
doaj   +1 more source

A specific example of our predictions for CTCF ChIA-PET interactions on chromosome 1 in GM12878 at 10-kb resolution.

, 2023
From top to bottom: the KR-normalized Hi-C, the CTCF coverage at 10-kb resolution, the heat map for ground-truth ChIA-PET interactions, and the heat map for our predicted ChIA-PET interactions.
Zheng Wang (25883), Tong Liu (107783)
core   +1 more source