Results 61 to 70 of about 346,815 (169)

Going beyond the borders : field-of-view extension in MR/PET hybrid imaging [PDF]

, 2012
The recent combination of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) is of emerging interest in clinical routine. On the one hand, MRI is a widely-used diagnostic tool in medical practice.
Blumhagen, Jan Ole
core   +1 more source

Super-resolution visualization of chromatin loop folding in human lymphoblastoid cells using interferometric photoactivated localization microscopy

Scientific Reports, 2022
The three-dimensional (3D) genome structure plays a fundamental role in gene regulation and cellular functions. Recent studies in 3D genomics inferred the very basic functional chromatin folding structures known as chromatin loops, the long-range ...
Zofia Parteka-Tojek, Jacqueline Jufen Zhu, Byoungkoo Lee, Karolina Jodkowska, Ping Wang, Jesse Aaron, Teng-Leong Chew, Krzysztof Banecki, Dariusz Plewczynski, Yijun Ruan   +9 more
doaj   +1 more source

Chromatin interaction neural network (ChINN): a machine learning-based method for predicting chromatin interactions from DNA sequences

Genome Biology, 2021
Chromatin interactions play important roles in regulating gene expression. However, the availability of genome-wide chromatin interaction data is limited.
Fan Cao, Yu Zhang, Yichao Cai, Sambhavi Animesh, Ying Zhang, Semih Can Akincilar, Yan Ping Loh, Xinya Li, Wee Joo Chng, Vinay Tergaonkar, Chee Keong Kwoh, Melissa J. Fullwood   +11 more
doaj   +1 more source

Asthma Therapies on Pulmonary Tuberculosis Pneumonia in Predominant Bronchiectasis–Asthma Combination

Frontiers in Pharmacology, 2022
Background: It is sometimes difficult to distinguish between asthma and bronchiectasis as their symptoms overlap, and these two diseases are associated with pulmonary tuberculosis (PTB) or pneumonia.Objective: The purpose of this study is to determine ...
Jun-Jun Yeh, Jun-Jun Yeh, Hui-Chuan Lin, Yu-Cih Yang, Yu-Cih Yang, Chung-Y. Hsu, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao, Chia-Hung Kao   +9 more
doaj   +1 more source

Chromatin Accessibility and Interactions in the Transcriptional Regulation of T Cells

Frontiers in Immunology, 2018
During T cell differentiation and activation, specific stimuli, and a network of transcription factors (TFs) are involved in orchestrating chromatin accessibility, establishing enhancer-promoter interactions, and regulating gene expression. Over the past
Peng Li, Warren J. Leonard
doaj   +1 more source

HiCuT: An efficient and low input method to identify protein-directed chromatin interactions.

PLoS Genetics, 2022
3D genome organization regulates gene expression, and disruption of these long-range (>20kB) DNA-protein interactions results in pathogenic phenotypes.
Satish Sati, Parker Jones, Hali S Kim, Linda A Zhou, Emmanuel Rapp-Reyes, Thomas H Leung   +5 more
doaj   +1 more source

HIFI: estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution

Genome Biology, 2020
Hi-C is a popular technique to map three-dimensional chromosome conformation. In principle, Hi-C’s resolution is only limited by the size of restriction fragments.
Christopher JF Cameron, Josée Dostie, Mathieu Blanchette   +2 more
doaj   +1 more source

Emprego da tecnologia supercrítica para a valorização do resíduo de semente de chia (Salvia hispanica) [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2014.A chia (Salvia hispanica) é uma planta cultivada nas Américas do Sul e Central, cuja semente é ...
Guindani, Camila
core  

The co-enrichment of transcription factors on identified chromatin loops in H1-ESC with CTCF ChIA-PET training model.

, 2022
The co-enrichment of transcription factors on identified chromatin loops in H1-ESC with CTCF ChIA-PET training model.
Qinhu Zhang (12219347), Kyungsook Han (19287), Ying He (125930), Zhen Cui (2966148), De-Shuang Huang (396909), Siguo Wang (12219350), Zhenghao Guo (7238795)   +6 more
core   +1 more source

PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence.

PLoS ONE, 2020
Enhancers are powerful and versatile agents of cell-type specific gene regulation, which are thought to play key roles in human disease. Enhancers are short DNA elements that function primarily as clusters of transcription factor binding sites that are ...
Caitlin Mills, Anushya Muruganujan, Dustin Ebert, Crystal N Marconett, Juan Pablo Lewinger, Paul D Thomas, Huaiyu Mi   +6 more
doaj   +1 more source