Results 61 to 70 of about 350,763 (258)

Rescue with an anti-inflammatory peptide of chickens infected H5N1 avian flu [PDF]

, 2009
Chickens suffering from avian flu caused by H5N1 influenza virus are destined to die within 2 days due to a systemic inflammatory response. Since HVJ infection (1,2) and influenza virus infection (3,4) cause infected cells to activate homologous serum ...
Alan A. Okada, Ekowati E. Handharyani, Hidechika H. Okada, Kazuhide K. Adachi, Masaki M. Imai, Noriko N. Okada, Retno Damajanti R. D. Soejoedono, Yasuhiro Tsukamoto   +7 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Chimeric Chickens and Their Use in Manipulation of the Chicken Genome

Poultry Science, 1993
Germline chimeric chickens can be made by injecting dispersed cells from Stage X blastoderms into recipient embryos at an equivalent stage of development. Colonization of the chimera by donor-derived cells is facilitated when the recipient embryo is compromised by exposure to irradiation prior to injection of the donor cells.
Robert J. Etches, Ann K. Toner, A. M. Verrinder Gibbins, Mary Ellen Clark, R. A. Fraser, R. S. Carsience   +5 more
openaire   +2 more sources

Domestic chickens activate a piRNA defense against avian leukosis virus [PDF]

, 2017
PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens.
Anai, Aravin, Aravin, Aravin, Assis, Baluda, Bao, Bartel, Benkel, Bolisetty, Boyce-Jacino, Boyce-Jacino, Brawand, Brennecke, Carmell, Cenik, Cenik, Chen, Chirn, Crittenden, Dempster, Eickbush, Eriksson, Fadly, Fagegaltier, Farazi, Feschotte, Flemr, Frisby, Frost, Gao, Ghildiyal, Gifford, Goic, Gunawardane, Guo, Haas, Han, Hayward, Houwing, Houwing, Ingolia, Ingolia, International Chicken Genome Sequencing Consortium, Johnson, Jurka, Ka, Ka, Khurana, Kim, Kohany, Kojima, Kuhnlein, Kumar, Kumar, Kuramochi-Miyagawa, Kuramochi-Miyagawa, Lee, Levin, Lewinski, Li, Li, Li, Lim, Lin, Lu, Malik, Malone, McClintock, Meunier, Moore, Nawrocki, Necsulea, Oh, Paradis, Peirson, Pelechano, Reuter, Reuter, Ricci, Roberts, Robinson, Rosenkranz, Rutherford, Sacco, Saxe, Schlötterer, Shoji, Smit, Smith, Smith, Smith, Smith, Soper, Stehelin, Steitz, Stoye, Sumiyoshi, Tam, Tanaka, Tarlinton, Team, Temin, Tereba, Thompson, Thomson, Trapnell, Trapnell, Vandergon, Varmus, Wang, Wang, Watanabe, Weiss, Weiss, Weiss, West, Wichert, Wicker, Wilson, Yabuta, Zhang, Zhang, Zheng, Zhuang   +124 more
core   +2 more sources

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Testicular growth and comb and wattles development in three Italian chicken genotypes reared under free range conditions [PDF]

, 2015
Male chickens belonging to three Italian purebreds \u2013 Ermellinata di Rovigo (ER), Robusta lionata (RL) and Robusta maculata (RM) \u2013 were studied. All the birds were reared under the same rearing conditions (from May until autumn).
DE FASSI NEGRELLI RIZZI, Chiara, Verdiglione, Rina   +1 more
core   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Enzymes as Feed Additive to Aid in Responses Against Eimeria Species in Coccidia-Vaccinated Broilers Fed Corn-Soybean Meal Diets with Different Protein Levels [PDF]

, 2007
This research aimed to evaluate the effects of adding a combination of exogenous enzymes to starter diets varying in protein content and fed to broilers vaccinated at day of hatch with live oocysts and then challenged with mixed Eimeria spp. Five hundred
Clack, Beatrice A., Clemente-Hernandez, S., Kettunen, H., Makivuokko, H., Osborne, J., Oviedo Rondon, E. O., Parker, J., Pierson, E. M., Remus, J. C.   +8 more
core   +2 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source