Results 51 to 60 of about 99,250 (279)

Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia

Tropical Medicine and Infectious Disease, 2022
Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks.
Marsha Sinditia Santoso, Sotianingsih Haryanto, Fadil Rulian, Rahma F. Hayati, Amanda Kristiani, Rini Kartika, Benediktus Yohan, Martin L. Hibberd, R. Tedjo Sasmono   +8 more
doaj   +1 more source

Long-term Chikungunya sequelae and quality of life 2.5 years post-acute disease in a prospective cohort in Curaçao

PLoS Neglected Tropical Diseases, 2022
Background Little is known about the persistence and impact of non-rheumatic symptoms after acute chikungunya disease. We have studied the clinical presentation and long-term impact of rheumatic and non-rheumatic symptoms on health related quality of ...
Churnalisa Doran, J. Elsinga, Ante Fokkema, Kevin Berenschot, I. Gerstenbluth, A. Duits, Norédiz Lourents, Y. Halabi, J. Burgerhof, A. Bailey, A. Tami   +10 more
semanticscholar   +1 more source

Explorations on the antiviral potential of zinc and magnesium salts against chikungunya virus: implications for therapeutics

Frontiers in Cellular and Infection Microbiology
BackgroundChikungunya virus (CHIKV), which causes chikungunya fever, is an arbovirus of public health concern with no approved antiviral therapies. A significant proportion of patients develop chronic arthritis after an infection.
Kusuma Sai Davuluri, Shridhar Shukla, Mahadeo Kakade, Sarah Cherian, Sarah Cherian, Kalichamy Alagarasu, Kalichamy Alagarasu, Deepti Parashar, Deepti Parashar   +8 more
doaj   +1 more source

Clinical outcomes of chikungunya: A systematic literature review and meta-analysis

PLoS Neglected Tropical Diseases
Background Chikungunya is a viral disease caused by a mosquito-borne alphavirus. The acute phase of the disease includes symptoms such as fever and arthralgia and lasts 7–10 days. However, debilitating symptoms can persist for months or years.
Kris Rama, A. D. de Roo, Timon Louwsma, Hinko S Hofstra, Gabriel S Gurgel do Amaral, G. Vondeling, M. J. Postma, Roel D Freriks   +7 more
semanticscholar   +1 more source

Antivirals against the Chikungunya Virus

Viruses, 2021
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in recent decades, causing large-scale epidemics in many parts of the world.
Verena Battisti, E. Urban, T. Langer
semanticscholar   +1 more source

Genetic predisposition to chikungunya – a blood group study in chikungunya affected families

Virology Journal, 2009
Chikungunya fever is a viral disease transmitted to humans by the bite of CHIKV virus infected Aedes mosquitoes. During monsoon outbreak of chikungunya fever, we carried out the genetic predisposition to chikungunya in disease affected 100 families by ...
Ramakrishna Vadde, Sarojamma Vemula, Sudarsanareddy Lokireddy   +2 more
doaj   +1 more source

Mutation of CD2AP and SH3KBP1 binding motif in alphavirus nsP3 hypervariable domain results in attenuated virus [PDF]

, 2018
Infection by Chikungunya virus (CHIKV) of the Old World alphaviruses (family Togaviridae) in humans can cause arthritis and arthralgia. The virus encodes four non-structural proteins (nsP) (nsP1, nsp2, nsP3 and nsP4) that act as subunits of the virus ...
Aquilimeba, Muriel, Kasvandik, Sergo, Lulla, Aleksei, Lulla, Valeria, McInerney, Gerald M., Merits, Andres, Morro, Ainhoa Moliner, Mutso, Margit, Saul, Sirle, Smedberg, Cecilia, Tarve, Liisi, Teppor, Mona, Thaa, Bastian, Varjak, Margus   +13 more
core   +3 more sources

Durability of Functional SARS-CoV-2-Specific Immunological Memory and T Cell Response up to 8–9 Months Postrecovery From COVID-19

Journal of Immunology Research
Research on long-term follow-up in individuals who have recovered from coronavirus disease-19 (COVID-19) would yield insights regarding their immunity status and identify those who need booster vaccinations.
Diptee Trimbake, Dharmendra Singh, Yogesh Gurav K., Prasad Babar, Varsha Dange S., Anuradha S. Tripathy   +5 more
doaj   +1 more source

RNAi-Induced Gene Silencing against Chikungunya and COVID-19: What Have We Learned So Far, and What Is the Way Forward?

Viruses
RNA interference (RNAi) is a process in which small RNA molecules (such as small interfering RNAs or siRNAs) bind to specific messenger RNAs (mRNAs), leading to its degradation and inhibition of protein synthesis.
Kingshuk Panda, Kalichamy Alagarasu, Rajarshee Tagore, Mandar Paingankar, Satyendra Kumar, Manish Kumar Jeengar, Sarah Cherian, Deepti Parashar   +7 more
doaj   +1 more source

Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective

Scientific Reports, 2023
The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate.
Tao-Qian Tang, Rashid Jan, Adil Khurshaid, Zahir Shah, Narcisa Vrinceanu, Mihaela Racheriu   +5 more
doaj   +1 more source