Results 101 to 110 of about 19,855 (219)

Development of an enzyme-linked immunosorbent assay using recombinant protein antigen for the diagnosis of Chikungunya virus

Data in Brief, 2019
We describe here the development of an in-house enzyme linked immunosorbent assay (ELISA) for the diagnostic of Chikungunya virus (CHIKV) infections using a recombinant protein from CHIKV.
Flávia Fonseca Bagno, Lara Carvalho Godoi, Natalia Salazar, Glauco de Carvalho Pereira, Maria Marta Figueiredo, Flávio Guimarães da Fonseca   +5 more
doaj   +1 more source

Overview on Chikungunya Virus Infection: From Epidemiology to State-of-the-Art Experimental Models

Frontiers in Microbiology, 2021
Chikungunya virus (CHIKV) is currently one of the most relevant arboviruses to public health. It is a member of the Togaviridae family and alphavirus genus and causes an arthritogenic disease known as chikungunya fever (CHIKF).
L. E. C. Constant, B. Rajsfus, P. H. Carneiro, T. Sisnande, R. Mohana-Borges, Diego Allonso   +5 more
semanticscholar   +1 more source

Efficacy of a Combined Natural Extract of Turmeric (Curcuma longa) and Liquorice (Glycyrrhiza uralensis) Against Viral Haemorrhagic Septicaemia Virus in Olive Flounders (Paralichthys olivaceus)

Journal of Fish Diseases, Volume 49, Issue 1, January 2026.
ABSTRACT Viral haemorrhagic septicaemia virus (VHSV) causes a high mortality rate in cultured olive flounder, and effective treatment for VHSV infection is urgently required. Turmeric (Curcuma longa ) and liquorice (Glycyrrhiza uralensis) are well‐known medicinal plants with a variety of biological activities. Turmeric and liquorice extract combination
Su‐Mi Shin, Walimuni Randika Harshan Mendis, So Young Kang, Hyung Jae Jeong, Taeho Kim, Sung‐Ju Jung   +5 more
wiley   +1 more source

Chikungunya Virus in Febrile Humans and Aedes aegypti Mosquitoes, Yucatan, Mexico

Emerging Infectious Diseases, 2016
Chikungunya virus (CHIKV) was isolated from 12 febrile humans in Yucatan, Mexico, in 2015. One patient was co-infected with dengue virus type 1. Two additional CHIKV isolates were obtained from Aedes aegypti mosquitoes collected in the homes of patients.
Nohemi Cigarroa-Toledo, Bradley J. Blitvich, Rosa C. Cetina-Trejo, Lourdes G. Talavera-Aguilar, Carlos M. Baak-Baak, Oswaldo M. Torres-Chablé, Md-Nafiz Hamid, Iddo Friedberg, Pedro González-Martinez, Gabriela Alonzo-Salomon, Elsy P. Rosado-Paredes, Nubia Rivero-Cárdenas, Guadalupe C. Reyes-Solis, Jose A. Farfan-Ale, Julian E. Garcia-Rejon, Carlos Machain-Williams   +15 more
doaj   +1 more source

An Overview of Indian Biomedical Research on the Chikungunya Virus with Particular Reference to Its Vaccine, an Unmet Medical Need

Vaccines, 2023
Chikungunya virus (CHIKV) is an infectious agent spread by mosquitos, that has engendered endemic or epidemic outbreaks of Chikungunya fever (CHIKF) in Africa, South-East Asia, America, and a few European countries.
Muhammed Muhsin Varikkodan, Faisal Kunnathodi, Sarfuddin Azmi, Tzong-Yuan Wu   +3 more
doaj   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, Volume 8, Issue 12, December 2025.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design

Nature Communications, 2023
Arthritogenic alphaviruses are positive-strand RNA viruses that cause debilitating musculoskeletal diseases affecting millions worldwide. A recent discovery identified the four-and-a-half-LIM domain protein 1 splice variant A (FHL1A) as a crucial host ...
Wern Hann Ng, Xiang Liu, Zheng L. Ling, Camilla N. O. Santos, Lucas S. Magalhães, Andrew J. Kueh, Marco J. Herold, Adam Taylor, Joseph R. Freitas, Sandra Koit, Sainan Wang, Andrew R. Lloyd, Mauro M. Teixeira, Andres Merits, Roque P. Almeida, Nicholas J. C. King, Suresh Mahalingam   +16 more
doaj   +1 more source

Pathogenicity and virulence of chikungunya virus

Virulence
Chikungunya virus (CHIKV) is a mosquito-transmitted, RNA virus that causes an often-severe musculoskeletal illness characterized by fever, joint pain, and a range of debilitating symptoms.
Wesley Freppel, Laurie A Silva, Kenneth A. Stapleford, Lara J. Herrero   +3 more
semanticscholar   +1 more source

Advanced Electrochemical Genosensor for Zika Virus Detection in Biological Samples Based on Cysteamine‐Graphene Quantum Dots Bilayer

Electroanalysis, Volume 37, Issue 12, December 2025.
An electrochemical biosensor for Zika virus (ZIKV) detection is described. A DNA probe was immobilized on a gold electrode. After hybridization with the target (ZIKV), safranin was used as an intercalating indicator. Detection was performed by differential pulse voltammetry (DPV), where the current signal increases with the target concentration.
Luiz F. G. Luz, Márcia M. C. N. Soares, Ana G. Brito‐Madurro, João M. Madurro   +3 more
wiley   +1 more source